Natural medications are gaining popularity as people become more aware of their benefits and accept their use in modern medicine. Natural drugs have demonstrated extensive suitability as curative agents for various disorders due to their fewer side effects and toxicity. Scientists face a tremendous problem in developing accurate analytical techniques that can efficiently profile the contents of phytochemicals. This is in addition to quantitative studies of marker or bioactive chemicals and some other important ingredients. Natural medicines, on the other hand, lack standardized parameters. Standardization is a vital step towards the formation of a constant chemical profile, consistent biological activity, or just a quality assurance programme for the production and manufacturing of natural products. As a requirement for global harmonization, the WHO criteria for assessing the safety, efficacy, and quality of natural drugs are extremely important. Scientific research of some of the natural origin plants regarded in Ayurvedic Rasayana for their beneficial potential has generated good results. The number of plants with a potential immunomodulatory activity that has been cultivated using conventional or cell culture methods is standardized. This can help to portray and validate their usage in folk medicine in the early days, as well as give an establishment for future investigation. The goal of this chapter is to showcase the findings of research evidence on standardized natural plantorigin immunomodulators. The chapter also goes through biological screening strategies for diverse plant medications with the goal of revealing the immunomodulation mechanism. Researchers will hopefully be encouraged to pursue more research on medicinal plants with immunomodulatory potential as a result of this study.
Keywords: Immmunomodulators, Immunostimulants, Immunosuppressants, Natural Drugs, Plant Tissue Culture, Standardization.
