Due to the diversity of engineering disciplines involved in electrochemical
biosensor studies, it is essential to be familiar with some topics, including experimental
design, electrochemical laboratory tools, primary biology literature, and biological
elements, to understand this area perfectly. The purpose of this chapter is to provide a
quick review of these topics. In the section on the design of experiments (DOE), we
discuss the principles of DOE, different approaches, guidelines for designing, and the
DOE process. This section helps researchers to conduct studies systematically. After
that, electrochemical instrumentation will be discussed. Potentio stat structure and
function, elements of electrochemical cells, and experiments with two, three, and four
electrodes are the topics that will be addressed. The final section of this chapter will
introduce some basic biological concepts and elements.
Keywords: Biological element, Biosensor, DOE, Instrumentation, Practical Principles.
