“Caution is the parent of Safety”. Early-stage diagnosis of Cancer can
provide better medicinal therapeutic responses. Currently, a majority of cancer is
diagnosed after having metastasized throughout the body. This led to the urgent
requirement for potent and precise cancer detection methods for clinical diagnosis.
Over the last several decades, the majority of researchers have concentrated their
efforts on developing a potential rapid detection technique based on Biosensor
technology for a variety of frightening human health-related disorders, such as
cardiovascular disease, cancer, diabetes, and others. Significant advances were made in
a wide range of fields attributed to the designed techniques having enhanced
sensitivity, specificity, and repeatability. The development of diagnostic treatments in
medicine was aided by noteworthy advancements in other scientific fields, including
genetics, chemistry, micro-electrical engineering, and computational biology. As a
result, efficient, accurate, rapid, and steady sensing platforms have been successfully
developed for specific and ultrasensitive biomarker-based disease diagnostics.
Biosensors are analytical devices designed to detect biological analytes by converting
biological entities’ responses (DNA, RNA, Protein) into potent electrical signals. The
biosensor device combines a biological component with a physiochemical detector for
sensing an analyte (biological samples). The discovery of the Biosensor boosted the
potential clinical diagnosis of cancer at a large scale. Biosensors can be designed to
detect emerging cancer biomarkers and determine drug efficacy at various target sites.
Biosensor technology has the potential to be used as a diagnostic tool for accurate and
impressive cancer cell imaging, tracking cancer cell angiogenesis and metastasis, and
evaluating the efficacy of treatment for the disease. This chapter will provide a quick
overview of the challenges facing the early diagnosis of cancer, get through the depth
of how biosensor technology may be used as a reliable diagnostic tool, and highlight
potential uses for biosensor technology in the future.
Keywords: Biosensors, Cancer detection, Early-stage diagnosis, Nanotechnology, Oncogene.
