Neurodegenerative disorders
have been implicated as the cause of many devastating diseases that are
characterized by gradual loss of susceptible neurons, that are increasingly
rising the prevalence of neurodegenerative diseases globally; however, therapeutics
for them are lacking. There is an urgent need to develop an effective therapy
that can combat the menace caused by disorders of neurodegenerative origin such
as Alzheimer's and Parkinson’s diseases, stroke, and traumatic brain injury.
Peerreviewed articles were explored for the purpose of this review. Several
natural products from medicinal plants have been reported to have phytochemical
components with bioactive effects in addition to nutritional value. An appropriate
bioactive component is essential for a healthy lifestyle as it plays a
significant role in the modulation of neurodegenerative diseases. This review
covers the mechanism of action of neurodegenerative disorders and highlights
selected classes of bioactive compounds and their effects on neurodegenerative
disorders. The use of bioactive compounds in the management of
neurodegenerative diseases could solve the problem of the nonavailability of
therapy.
Keywords: Bioactive Compounds, Disease, Intervention, Neurodegenerative, Therapeutic.
