The multicomponent reactions (MCRs) are vital for producing structurally
varied molecular objects. Multicomponent reactions (MCRs) contain three or more
synthetic stages and are carried out without isolation of any intermediate, thus requiring
mild reaction conditions. They are eco-friendly and cost-effective, have a short reaction
time, produce higher yields, and require raw materials. The use of microwave
irradiation in green organic synthesis sustains some of the aims of “green and
sustainable chemistry.” It offers several benefits over the conventional approach in
reducing time, reaction rates, selectivity, product yields, etc. Consequently, the
preparation of various heterocycles using a one-pot multicomponent method combined
with the application of microwave irradiation is one of the best areas amongst synthetic
chemistry. The present study illustrates an overview of recent progress on microwaveirradiated, one-pot multicomponent synthesis of heterocycles.
Keywords: Benzoxazoles, Conventional Heating, Furans, Fused Heterocycles, Green Chemistry, Heating Mechanism, Heterocyclic Compounds, Imidazoles, Multicomponent Synthesis, Microwave Effects, Microwave Irradiation, One-pot Reaction, Pyrans, Pyridines, Pyrimidines, Pyrroles, Reaction selectivity, Spiroheterocycles, Thiazoles, Triazoles
