At present, we are in a crucial situation to find out and understand the
immune response for severe acute respiratory syndrome coronavirus inside of human
body systems. The novel coronavirus (SARS cov-2) has to cause 35 million infections
and more than 1 million deaths worldwide as on October, 2020, according to the WHO
dashboard. The explosive unfolds of SARS-CoV-2 indicate that a vaccine could be
required to cease this global pandemic. Progress in SARS-CoV-2 vaccine improvement
thus far has been faster than for some other pathogen in history. There were 42
vaccines in clinical research, and nearly 150 vaccines are in preclinical study. The
immunogenicity alone data will help to attain a goal of design and development of
good and safe vaccine averse to SARS CoV-2 infections in many countries and it also
helps to predict the efficacy of the COVID-19 vaccine. Still now, we do not have a
particular vaccine for COVID-19 infections, only we boost up our immune system to
reduce the Covid-19 infections. So, we must know about our immune systems as well
as the immunogenicity of the bio-active compounds for the prediction of the valuable
and most powerful vaccine. A vaccine against SARS CoV-2 must control the infection
and be capable of controlling the disease or transmission. For these reasons, we can
detail explaining about fundamentals and application of Immunogenicity and also
discuss its application to find out the potent SARS CoV-2-vaccine in this present study.
Keywords: Covid-19, Immune system, SARS CoV-2, Vaccine.