Today, massive investigations have been undertaken to boost the targetoriented distribution of drugs to maximize their therapeutic index. Cell targeting drug
delivery is a good candidate in exhibiting therapeutic effect to severe diseases such as
cancer; The extent to which the drug can achieve its intended goal is of the utmost
importance. This system is designed to aid a drug's ability to pass an obstacle that it might
not otherwise be able to pass through regular means; therefore, their impact is
pharmacokinetic. The drug's pharmacological effects should remain untouched, like its
pharmacodynamic structure. In some cases, the pharmaceutical delivery mechanism
has an effect on how the drug appears to work. Drugs must overcome numerous hurdles
that are on the way to the target tissue from the administration site. In certain cases, a
physically defensive barrier around the drug cargo is created to help the drug navigate
over certain barriers. The need for selective medication distribution has, therefore, been
well acknowledged in current drug therapy. Thus, in this chapter, we discuss the different
organelle targeting drug delivery systems and studies involved in it.
Keywords: Cell organelles, Targeted drug delivery, Vesicle based drug delivery.
