Mild cognitive impairment has usually been associated with aging, however,
in recent decades with the increase in the prevalence of pathologies such as obesity,
diabetes mellitus, cardiovascular diseases, and even spinal cord injury, it has become
evident that a significant percentage of people who suffer from one or more of these
diseases are at greater risk of suffering from some level of cognitive impairment that
can lead to the development of various types of dementia. In this chapter, we review
the main characteristics and mechanisms that promote the development of this type of
alteration in each of the mentioned pathologies and briefly describe the various ways in
which they have been approached.
Keywords: Amnesic Memory, aging, Cognitive Domains, Diabetes Mellitus,
Dysbiosis, Hypertension, Long-Term Potentiation, Low-Grade Inflammation,
Mild Cognitive Impairment, Neurogenesis, Non-Amnestic Memory, Obesity,
Stroke, Spinal Cord Injury.