Nanotechnology is a branch of science that deals with nanomaterials with a
size of less than 100nm. These nanoparticles have a wide variety of applications in the
field of bioimaging, biosensors, drug delivery, gene therapy, etc. The main advantage
of using nanoparticles is that they may be fabricated as desired depending upon the
area of application. The size, surface chemistry and physiochemical properties may be
changed as required by following the parameters of synthesis. Nanoparticles may also
help in RNAi therapy that delivers siRNA, shRNA and miRNAs to the target site. The
major drawback of using these RNA molecules in their bare form is the fragile nature
that makes them degradable by the enzymes in the blood vascular system. In this
regard, nanoparticles protect them from degradation as they may encapsulate the RNA
molecules within their structure. There are mainly three types of nanoparticles such as
inorganic, organic and polymeric nanoparticles. In this book, we are intended to discuss
the wide variety of nanoparticles that are used in biosensing, bioimaging, drug delivery,
gene therapy, immunotherapy and vaccination.
Keywords: Bioimaging, Biological property, Biosensor, Chemical property,
DNA, Electronic property, Immunotherapy, MiRNA, Nanocarrier, Nanomaterial,
Nanomedicine, Nanotechnology, Nanoparticle, Optical property, Physical
property, RNAi therapy, ShRNA, SiRNA, Theranostic, Vaccine.
