Chrysophyllum cainito L. is part of the family Sapotaceae and native to the
Greater Antilles and the West Indies. This specie is a medicinal plant used around the
world by many cultures, commonly known as “star apple” or “caimito”. Some studies
have reported that C. cainito possesses many pharmacological properties as
antidiabetic, anti-hypersensitivity, antihypertensive, anti-inflammatory, antimicrobial,
antinociceptive, antioxidant, gastroprotective and immunosuppressive. Also,
phytochemical evidence has revealed that the main secondary metabolites in C. cainito
are alkaloids, tannins, flavonoids, phenols, sterols, coumarins and triterpenes which are
responsible for their pharmacological benefits. In vitro and in vivo toxicology studies
have suggested human consumption of Chrysophyllum cainito leaves as safe. This
chapter includes scientific information of pharmacology, toxicology and
phytochemistry of C. cainito seeds, leaves, and fruits with the purpose to contribute
valuable scientific information to future research in drug development based on C.
cainito as a source of raw material.
Keywords: Antidiabetic, Anti-inflammatory, Antimicrobial, Antinociceptive,
Antioxidant, Chrysophyllum cainito L., Immunosuppressive, Medicinal use,
Pharmacology Phytochemicals, Toxicity.
