Raman spectroscopy is a significant characterization technique using
inelastic scattering of light associated with molecular vibration to gather information
about chemical fingerprints of tissues, cells or biofluids. Lack of sample preparation
including chemical specificity and the ability to use advanced techniques in the visible
or near-infrared spectral range have led versatility in biological applications of Raman
spectroscopy. By Raman spectroscopy, the changes caused by diseases in tissues and
organs can be accurately investigated and it is fast, non-invasive, economic and highly
specific in comparison to other diagnostic and imaging techniques. It can provide
quantitative molecular information for an objective diagnosis. Raman spectroscopy can
measure both chemical and morphological information in samples and provide
objective diagnosis for independent tissue samples of new patients. Some specific
techniques and applications presented in this chapter which will demonstrate the
potential of Raman spectroscopy for medical diagnostics, as well as the versatile
interest in healthcare service.
Keywords: Biomedical applications, Instrumentation, Raman spectroscopy,
Structure determination.