Enzyme inhibitors are widely prescribed drugs for many diseases including
neurological disorders and today most of the drugs are enzyme inhibitors and are in the
clinical/pre-clinical phase of the drug discovery. For many of the neurological
disorders, especially neurodegenerative disorders, only symptomatic therapy is
available rather than the therapy based on an understanding of the mechanism of these
diseases. In this case, enzyme inhibitors become the solution as they inhibit the action
of enzymes whose abnormal activity may be one of the causes of the disease. They also
halt the progression of the disease and alleviate the symptoms. This chapter focuses on
some of the enzyme inhibitors that have been prescribed as drugs for neurological
disorders, their mechanism of action and discuss some inhibitors that are still in their
research level of development.
Keywords: Drug discovery, Enzyme Inhibitors, Neurological disorders,
Symptomatic therapy.
