Neurodegenerative diseases have been known to exist in the human
population for a long time, yet most of them do not have a cure even until now. With
the recent surge of nanotechnology and its applications to physiology as nanomedicine,
a new hope for a better future has been offered. Nanomedicine has opened up many
areas of further research that can lead us to a probable cure for these diseases. This
review particularly focuses on Alzheimer’s disease (AD), which is a progressive
neurodegenerative disorder. AD primarily affects the cerebral cortex in the forebrain
and the hippocampus in the midbrain. According to the World Alzheimer’s report,
there are 46.8 million AD patients worldwide as of 2016 with a high probability of this
statistic becoming double in the next two decades. For understanding this crucial
situation, studying the pathology of AD, and recent advancements in the treatment of
AD, specifically through nanomedicine becomes extremely important. Through this
review, we intend to explore all the relevant aspects in relation to nanotechnological
advancements for the treatment of Alzheimer’s disease.
Keywords: Alzheimer’s disease, Drug Delivery System, Lipid-based
Nanoparticles, Neurodegenerative diseases, Nanoparticles, Nanomedicine,
Neuroinflammation, Polymeric Nanoparticles.
