Hypertrophic cardiomyopathy (HCM) is an inherited autosomal dominant
genetic disease characterised by asymmetrical increased wall thickness of a non-dilated
LV chamber. It has a diverse natural history which is attributed to its heterogeneous
clinical presentation. HCM could be diagnosed clinically, by ECG changes and
definitely by echocardiographic characteristics. Pharmacological therapy has an
important role in the management of HCM. Alcohol septal ablation and pacing may be
used in certain conditions. Septal myectomy, Morrow procedure, is indicated to reduce
persistent gradient and alleviate symptoms refractory to medications.
Keywords: Cardiomyopathy, Congenital Heart Disease, Dual Chamber Pacing,
End-Stage Heart Failure, Gene Mutation, Hypertrophy, Myectomy, Morrow,
Outflow Obstruction, Septal Ablation, Sudden Cardiac Death.
