Two commonly used approaches for fabrication of plasmonic nanostructures: self assembled monolayer and
electrochemistry techniques were introduced. The bottom-up approach has advantages of cost effective, large area fabrication, and
simple process. But it is chemistry-based process, and thus has shortages of low repeatability, unstable, and low uniformity. It is
suitable for fabrication of micro-/nanostructures which can be used as biosensors in life science.