Possessing excellent bio-compatibility and mechanical performance, Ti-6Al-
4V (TC4) alloy is widely used as implant. Aiming at solving the problem of poor
surface wear properties and improving bio-compatibility of TC4 alloy, friction stir
processing(FSP) is applied to it filled with TiO2 powder in the groove to realize surface
modification and build nano-sized composite biomedical material. Change in
microstructure and its relationship with mechanical performance such as hardness will
be discussed. A series of experiments in biology, including cytotoxicity test, cell
culture, adhesion, proliferation and alkaline phosphatase activity is carried out to verify
bio-compatibility of the material, compared with original TC4. The improved material
is expected to provide a better environment for cells to grow.
Keywords: Bio-compatibility, Biomedical titanium alloy, Friction stir process,
Nano-sized composite layer, Surface modification.
