Long-term survival of scaffolds depends on having no detrimental immune
response. Designing biomaterials that are able to modulate host responses and thus
support the healing process is essential for tissue remodeling. In depth understanding of
immune response to the biomaterials and their transplanted cells is important since the
interaction between host response and transplanted cells demonstrates the
biocompatibility of the implanted scaffold. In this chapter, we mainly aim to focus on
innate and adaptive immune response and wound healings processes. In detail we
discuss about variables that effect on the immune responses and the current strategies
for modulating.
Keywords: Immune responses, Scaffold, Tissue engineering.
