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摘要
卵巢癌是所有妇科癌症死亡的主要原因。到目前为止,还没有一个可靠的,特定的筛选程序来检测卵巢癌。卵巢癌的危险因素包括可修改和不可更改的因素。卵巢癌预防计划的主要目标是显著降低卵巢癌和其他癌症(如br)的风险。东方和/或腹膜癌。非手术预防方法,如口服避孕药、分娩和母乳喂养,已被证明对卵巢癌具有高度的保护作用。发展。靶向性炎症也被报道与卵巢癌的保护趋势相关,并且可以通过非甾体类抗炎药物(Nsa)来实现。例如阿司匹林或改变生活方式或两者兼而有之。生活方式的改变,包括定期运动、补充抗氧化剂和抗炎成分的健康饮食可以降低r。ISK的疾病甚至更远。手术保护方法包括输卵管结扎术、子宫切除术和预防性双侧输卵管卵巢切除术,前者是最有效的方法。防止卵巢癌。更好地了解卵巢癌的危险因素和目前预防卵巢癌的方法,可以提高人们对卵巢癌的认识,有助于降低卵巢癌的发病率。伊恩癌症,提高5年生存率,降低总人群的死亡率,特别是在高危卵巢癌人群中。 这篇评论是一个ATTEM概述卵巢癌预防的潜在方案和潜在的挑战。
关键词: 阿司匹林,母乳喂养,避孕药,卵巢癌,分娩,体力活动,预防性手术。
Current Cancer Drug Targets
Title:Towards Prevention of Ovarian Cancer
Volume: 18 Issue: 6
关键词: 阿司匹林,母乳喂养,避孕药,卵巢癌,分娩,体力活动,预防性手术。
摘要: Ovarian cancer is the leading cause of death of all gynaecological cancers. To date, there is no reliable, specific screening procedure for detecting ovarian cancer. The risk factors of ovarian cancer include modifiable and non-modifiable factors. The main goal of the ovarian cancer prevention program is to significantly reduce the risk of development of ovarian cancer and other cancers such as breast and/or peritoneal cancer. The application of non-surgical preventive approaches such as oral contraceptives, parity and breastfeeding has been shown to be highly protective against ovarian cancer development. Targeting inflammation has been also reported to be associated with a protective trend against ovarian cancer and can be achieved through either non-steroidal antiinflammatory drugs (NSAIDs) such as aspirin or lifestyle modifications or both. Lifestyle modification that includes regular exercise, healthy diet supplemented with anti-oxidants and antiinflammatory elements reduces the risk of the disease even further. Surgical protective approaches include; tubal ligation, hysterectomy and prophylactic bilateral salpingo-oophorectomy and the former is the most effective approach to protect against ovarian cancer. A better understanding of the risk factors of ovarian cancer and the current approaches to prevent it may increase the awareness and help decrease the incidence of ovarian cancer, increase the five-year survival rate and decrease the mortality rate significantly in the general population especially among those at high risk for ovarian cancer. This review is an attempt to outline a potential program of ovarian cancer prevention and the potential challenges.
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Cite this article as:
Towards Prevention of Ovarian Cancer, Current Cancer Drug Targets 2018; 18 (6) . https://dx.doi.org/10.2174/1568009618666180102103008
DOI https://dx.doi.org/10.2174/1568009618666180102103008 |
Print ISSN 1568-0096 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5576 |
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