Abstract
Background: Hemodynamics during dynamic exercise is finely regulated by some neural mechanisms. One of these mechanisms is the metabolic part of the exercise pressor reflex, i.e. the muscle metaboreflex. Hemodynamic response during the metaboreflex is characterised by the recruitment of the reserves in cardiac inotropism, pre-load, after-load and chronotropism. If one of these reserves is exhausted, then the cardiovascular response is achieved by recruiting one of the other reserves, thereby indicating a remarkable plasticity of the control of circulation.
Conclusion: In this review, the effects of a number of cardiovascular diseases – such as heart failure, heart failure with preserved ejection fraction, hypertension, type 1 and type 2 diabetes mellitus, obesity and metabolic syndrome – on hemodynamics during the metaboreflex are reviewed.
Keywords: Inotropism, preload, afterload, chronotropism, systemic vascular resistance, Hemodynamics.
Current Cardiology Reviews
Title:The Impact of Cardiovascular Diseases on Cardiovascular Regulation During Exercise in Humans: Studies on Metaboreflex Activation Elicited by the Post-exercise Muscle Ischemia Method
Volume: 13 Issue: 4
Author(s): Antonio Crisafulli*
Affiliation:
- Department of Medical Sciences and Public Health, Sports Physiology Lab., University of Cagliari, Via Porcell 4, 09124 Cagliari,Italy
Keywords: Inotropism, preload, afterload, chronotropism, systemic vascular resistance, Hemodynamics.
Abstract: Background: Hemodynamics during dynamic exercise is finely regulated by some neural mechanisms. One of these mechanisms is the metabolic part of the exercise pressor reflex, i.e. the muscle metaboreflex. Hemodynamic response during the metaboreflex is characterised by the recruitment of the reserves in cardiac inotropism, pre-load, after-load and chronotropism. If one of these reserves is exhausted, then the cardiovascular response is achieved by recruiting one of the other reserves, thereby indicating a remarkable plasticity of the control of circulation.
Conclusion: In this review, the effects of a number of cardiovascular diseases – such as heart failure, heart failure with preserved ejection fraction, hypertension, type 1 and type 2 diabetes mellitus, obesity and metabolic syndrome – on hemodynamics during the metaboreflex are reviewed.
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Crisafulli Antonio *, The Impact of Cardiovascular Diseases on Cardiovascular Regulation During Exercise in Humans: Studies on Metaboreflex Activation Elicited by the Post-exercise Muscle Ischemia Method, Current Cardiology Reviews 2017; 13 (4) . https://dx.doi.org/10.2174/1573403X13666170804165928
DOI https://dx.doi.org/10.2174/1573403X13666170804165928 |
Print ISSN 1573-403X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6557 |
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