Abstract
Malignant pleural mesothelioma is an asbestos-linked cancer associated with a very poor prognosis. Surgical interventions form an important aspect of the management of this aggressive form of cancer. However, debate continues regarding the different treatment options available. Video assisted thoracoscopic surgery (VATS) has been the procedure of choice for the diagnosis of malignant pleural mesothelioma as big samples can be taken from multiple areas of the chest under direct vision. It may also be used as a palliative procedure to drain pleural effusion and perform pleurodesis. Other surgical options include extrapleural pneumonectomy, radical pleurectomy or extended pleurectomy decortication and pleurectomy and decortication. Frequently, these surgical procedures are performed in conjunction with chemotherapy and/or radiotherapy. In this review we will discuss the developments and remaining controversies of surgery in the context of malignant pleural mesothelioma.
Keywords: Asbestos, cancer, malignant pleural mesothelioma, prognosis.
Current Respiratory Medicine Reviews
Title:Surgical Options for Management of Malignant Pleural Mesothelioma in the Current Era
Volume: 12 Issue: 4
Author(s): Mahmoud Loubani, Syed S. Qadri, Azar Hussain, Mubarak A. Chaudhry and Jack A. Kastelik
Affiliation:
Keywords: Asbestos, cancer, malignant pleural mesothelioma, prognosis.
Abstract: Malignant pleural mesothelioma is an asbestos-linked cancer associated with a very poor prognosis. Surgical interventions form an important aspect of the management of this aggressive form of cancer. However, debate continues regarding the different treatment options available. Video assisted thoracoscopic surgery (VATS) has been the procedure of choice for the diagnosis of malignant pleural mesothelioma as big samples can be taken from multiple areas of the chest under direct vision. It may also be used as a palliative procedure to drain pleural effusion and perform pleurodesis. Other surgical options include extrapleural pneumonectomy, radical pleurectomy or extended pleurectomy decortication and pleurectomy and decortication. Frequently, these surgical procedures are performed in conjunction with chemotherapy and/or radiotherapy. In this review we will discuss the developments and remaining controversies of surgery in the context of malignant pleural mesothelioma.
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Loubani Mahmoud, Qadri S. Syed, Hussain Azar, Chaudhry A. Mubarak and Kastelik A. Jack, Surgical Options for Management of Malignant Pleural Mesothelioma in the Current Era, Current Respiratory Medicine Reviews 2016; 12 (4) . https://dx.doi.org/10.2174/1573398X13666161230162248
DOI https://dx.doi.org/10.2174/1573398X13666161230162248 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
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Chronic obstructive pulmonary disease (COPD) from childhood to adulthood: from the past to the future
Chronic obstructive pulmonary disease (COPD) is one of the three leading causes of death worldwide, with a major prevalence in low- and middle-income countries, resulting in a high social and economic cost. It is a heterogeneous respiratory disease, treatable and preventable, that causes persistent and often progressive airway obstruction in ...read more
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