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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Review Article

Progress in Polysaccharide Derivatization and Properties

Author(s): Qilin Tang and Gangliang Huang

Volume 16, Issue 15, 2016

Page: [1244 - 1257] Pages: 14

DOI: 10.2174/1389557516999160612164003

Price: $65

Abstract

Polysaccharides and their derivatives have opened up new industrial field because of their special biochemical functions. Their biological immune, biological inhibition, antioxidant and anticoagulant properties have begun to help people enhance their physique, the fight against aging. Molecular modification is an important way to study the structure-activity relationship of polysaccharides which should be focused on. After molecular modification, various derivatives of different types of structures and biological activities are gained. Chemical modification of polysaccharides, e.g., carboxymethylation, sulfonylation, phosphorylation, acetylation, and hydroxypropylation, cationic or other derivatives, can improve their bioavailability and applications in different biological systems.

Keywords: Anticoagulant, anti-tumor, biological activities, derivatives, polysaccharides.


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