Abstract
Polysaccharides and their derivatives have opened up new industrial field because of their special biochemical functions. Their biological immune, biological inhibition, antioxidant and anticoagulant properties have begun to help people enhance their physique, the fight against aging. Molecular modification is an important way to study the structure-activity relationship of polysaccharides which should be focused on. After molecular modification, various derivatives of different types of structures and biological activities are gained. Chemical modification of polysaccharides, e.g., carboxymethylation, sulfonylation, phosphorylation, acetylation, and hydroxypropylation, cationic or other derivatives, can improve their bioavailability and applications in different biological systems.
Keywords: Anticoagulant, anti-tumor, biological activities, derivatives, polysaccharides.
Mini-Reviews in Medicinal Chemistry
Title:Progress in Polysaccharide Derivatization and Properties
Volume: 16 Issue: 15
Author(s): Qilin Tang and Gangliang Huang
Affiliation:
Keywords: Anticoagulant, anti-tumor, biological activities, derivatives, polysaccharides.
Abstract: Polysaccharides and their derivatives have opened up new industrial field because of their special biochemical functions. Their biological immune, biological inhibition, antioxidant and anticoagulant properties have begun to help people enhance their physique, the fight against aging. Molecular modification is an important way to study the structure-activity relationship of polysaccharides which should be focused on. After molecular modification, various derivatives of different types of structures and biological activities are gained. Chemical modification of polysaccharides, e.g., carboxymethylation, sulfonylation, phosphorylation, acetylation, and hydroxypropylation, cationic or other derivatives, can improve their bioavailability and applications in different biological systems.
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Cite this article as:
Tang Qilin and Huang Gangliang, Progress in Polysaccharide Derivatization and Properties, Mini-Reviews in Medicinal Chemistry 2016; 16 (15) . https://dx.doi.org/10.2174/1389557516999160612164003
DOI https://dx.doi.org/10.2174/1389557516999160612164003 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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