Abstract
Antibiotics are one of the most important discoveries in the 20th century and have been widely used for treating animal diseases in the 21st century. However, antibiotic resistance among bacterial pathogens and widespread concerns regarding their use in animals has received great attention all over the world. Great attention has focused on scientific breakthroughs of the alternatives to antibiotics. Various materials such as enzymes, prebiotics, probiotics, minerals, antimicrobial peptides, acidifiers, plants and plant extracts have been tested as possible antibiotics alternatives. Owing to their effects on intestinal microbiota and immune function, research efforts have been conducted on the application of these feed supplements. This review highlights promising research results about the alternatives to antibiotics in animal husbandry that are expected to beneficially limit the adverse effects of antibiotics and ensure the safety of animal-derived foods and the environment.
Keywords: Animal husbandry, antibiotic alternatives, application, immune function, microbiota, regulation pathway.
Current Protein & Peptide Science
Title:The Signal Pathway of Antibiotic Alternatives on Intestinal Microbiota and Immune Function
Volume: 17 Issue: 8
Author(s): Ji Wang, Meng Han, Guolong Zhang, Shiyan Qiao, Defa Li and Xi Ma
Affiliation:
Keywords: Animal husbandry, antibiotic alternatives, application, immune function, microbiota, regulation pathway.
Abstract: Antibiotics are one of the most important discoveries in the 20th century and have been widely used for treating animal diseases in the 21st century. However, antibiotic resistance among bacterial pathogens and widespread concerns regarding their use in animals has received great attention all over the world. Great attention has focused on scientific breakthroughs of the alternatives to antibiotics. Various materials such as enzymes, prebiotics, probiotics, minerals, antimicrobial peptides, acidifiers, plants and plant extracts have been tested as possible antibiotics alternatives. Owing to their effects on intestinal microbiota and immune function, research efforts have been conducted on the application of these feed supplements. This review highlights promising research results about the alternatives to antibiotics in animal husbandry that are expected to beneficially limit the adverse effects of antibiotics and ensure the safety of animal-derived foods and the environment.
Export Options
About this article
Cite this article as:
Wang Ji, Han Meng, Zhang Guolong, Qiao Shiyan, Li Defa and Ma Xi, The Signal Pathway of Antibiotic Alternatives on Intestinal Microbiota and Immune Function, Current Protein & Peptide Science 2016; 17 (8) . https://dx.doi.org/10.2174/1389203717666160526123351
DOI https://dx.doi.org/10.2174/1389203717666160526123351 |
Print ISSN 1389-2037 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5550 |
Call for Papers in Thematic Issues
Advancements in Proteomic and Peptidomic Approaches in Cancer Immunotherapy: Unveiling the Immune Microenvironment
The scope of this thematic issue centers on the integration of proteomic and peptidomic technologies into the field of cancer immunotherapy, with a particular emphasis on exploring the tumor immune microenvironment. This issue aims to gather contributions that illustrate the application of these advanced methodologies in unveiling the complex interplay ...read more
Artificial Intelligence for Protein Research
Protein research, essential for understanding biological processes and creating therapeutics, faces challenges due to the intricate nature of protein structures and functions. Traditional methods are limited in exploring the vast protein sequence space efficiently. Artificial intelligence (AI) and machine learning (ML) offer promising solutions by improving predictions and speeding up ...read more
Nutrition and Metabolism in Musculoskeletal Diseases
The musculoskeletal system consists mainly of cartilage, bone, muscles, tendons, connective tissue and ligaments. Balanced metabolism is of vital importance for the homeostasis of the musculoskeletal system. A series of musculoskeletal diseases (for example, sarcopenia, osteoporosis) are resulted from the dysregulated metabolism of the musculoskeletal system. Furthermore, metabolic diseases (such ...read more
Protein Folding, Aggregation and Liquid-Liquid Phase Separation
Protein folding, misfolding and aggregation remain one of the main problems of interdisciplinary science not only because many questions are still open, but also because they are important from the point of view of practical application. Protein aggregation and formation of fibrillar structures, for example, is a hallmark of a ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
The Metastatic Process: Methodological Advances and Pharmacological Challenges
Current Medicinal Chemistry Potential Role of Natural Compounds as Anti-Angiogenic Agents in Cancer
Current Vascular Pharmacology Green Tea Catechins as Novel Antitumor and Antiangiogenic Compounds
Current Medicinal Chemistry - Anti-Cancer Agents Understanding Mouse Skin Carcinogenesis through Transgenic Approaches
Current Genomics Merkel Cell Carcinoma – Current State and the Future
Current Cancer Therapy Reviews Current Strategies for Probing Substrate Specificity of Proteases
Current Medicinal Chemistry Immunotherapy for Uveal Melanoma - Current Knowledge and Perspectives
Current Medicinal Chemistry Recent Patents in Circulating Cell-Free Tumor DNA as Biomarker in Cancer
Recent Patents on Biomarkers Development of a Substrate Identification Method for Human Scp1 Phosphatase Using Phosphorylation Mimic Phage Display
Protein & Peptide Letters Secretory Clusterin as a Novel Molecular-targeted Therapy for Inhibiting Hepatocellular Carcinoma Growth
Current Medicinal Chemistry Moving Towards Dawn: KRas Signaling and Treatment in Pancreatic Ductal Adenocarcinoma
Current Molecular Pharmacology Evaluation of Vitamin C as a Personalized Adjuvant Medicine: Pharmacogenomic Studies
Current Pharmacogenomics and Personalized Medicine Synthesis and <i>In Silico</i> Studies of C-4 Substituted Coumarin Analogues as Anticancer Agents
Current Computer-Aided Drug Design Strategies for Targeting the Multidrug Resistance-1 (MDR1)/P-gp Transporter in Human Malignancies
Current Cancer Drug Targets Tumor Vasculature Targeting Through NGR Peptide-Based Drug Delivery Systems
Current Pharmaceutical Biotechnology Molecular Modeling Studies of ABC Transporters Involved in Multidrug Resistance
Mini-Reviews in Medicinal Chemistry Monoterpenes as Perspective to Chronic Pain Management: A Systematic Review
Current Drug Targets Vascular Endothelial Growth Factor Receptors [VEGFR] as Target in Breast Cancer Treatment: Current Status in Preclinical and Clinical Studies and Future Directions
Current Topics in Medicinal Chemistry Vpr-Induced DNA Double-Strand Breaks: Molecular Mechanism and Biological Relevance
Current HIV Research Insights into Targeting NEMO for Pharmacological Regulation
Current Drug Targets