Abstract
Background: In the last years, the production and applications of nanoparticles based on iron oxides in the field of biomedicine presented a great interest due to their particular properties. Because of the expansion of the pharmaceutical industry numerous new systems for drugs delivery have appeared, and those centered on magnetic nanoparticles are in a particular attention and in different promising developmental stages.
Objective: In this mini review, some representative, interesting and feasible magnetic nanostructures obtained recently (from last 5-6 years) with possible use in antitumor/anticancer therapy are presented.
Results: The synthesis of these nanostructures with magnetic properties implies very simple assembling procedures and presents one of the lowest cytotoxic profiles. Magnetic nanostructures displayed possible appliance in a large diversity of biotechnological and medical fields, both for diagnose and therapy.
Conclusion: Different types of magnetic nano-carriers loaded with different antitumor/anticancer agents and the cases tested in vivo are considered.
Keywords: Functionalized magnetic nanostructures, anticancer therapy, drug delivery, combined drug release, imaging and hyperthermia.
Current Drug Targets
Title:Functionalized Magnetic Nanostructures for Anticancer Therapy
Volume: 19 Issue: 3
Author(s): Eugenia Dumitra Teodor*, Florentina Gatea, Anton Ficai and Gabriel Lucian Radu
Affiliation:
- Centre of Bioanalysis, National Institute for Biological Sciences, Bucharest,Romania
Keywords: Functionalized magnetic nanostructures, anticancer therapy, drug delivery, combined drug release, imaging and hyperthermia.
Abstract: Background: In the last years, the production and applications of nanoparticles based on iron oxides in the field of biomedicine presented a great interest due to their particular properties. Because of the expansion of the pharmaceutical industry numerous new systems for drugs delivery have appeared, and those centered on magnetic nanoparticles are in a particular attention and in different promising developmental stages.
Objective: In this mini review, some representative, interesting and feasible magnetic nanostructures obtained recently (from last 5-6 years) with possible use in antitumor/anticancer therapy are presented.
Results: The synthesis of these nanostructures with magnetic properties implies very simple assembling procedures and presents one of the lowest cytotoxic profiles. Magnetic nanostructures displayed possible appliance in a large diversity of biotechnological and medical fields, both for diagnose and therapy.
Conclusion: Different types of magnetic nano-carriers loaded with different antitumor/anticancer agents and the cases tested in vivo are considered.
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Cite this article as:
Teodor Dumitra Eugenia*, Gatea Florentina, Ficai Anton and Radu Lucian Gabriel, Functionalized Magnetic Nanostructures for Anticancer Therapy, Current Drug Targets 2018; 19 (3) . https://dx.doi.org/10.2174/1389450117666160208145835
DOI https://dx.doi.org/10.2174/1389450117666160208145835 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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