Abstract
Acute and sustained activation of the sympathetic nervous system are clinical hallmarks of both obstructive and central sleep apnea. Conversely, their treatment has been shown to reverse these abnormalities. The objectives of this brief review are to summarize: 1) present knowledge concerning the mechanisms, magnitude and consequences of night- and day-time sympathetic nervous system activation in patients with these sleep-related breathing disorders; and 2) the impact on the sympathetic nervous system and on blood pressure of their specific treatment.
Keywords: Adaptive servo-ventilation, central sleep apnea, continuous positive airway pressure, heart failure, hypertension, muscle sympathetic nerve activity, obstructive sleep apnea, sleep.
Current Hypertension Reviews
Title:Sympathetic Nervous System in Patients with Sleep Related Breathing Disorders
Volume: 12 Issue: 1
Author(s): John S. Floras
Affiliation:
Keywords: Adaptive servo-ventilation, central sleep apnea, continuous positive airway pressure, heart failure, hypertension, muscle sympathetic nerve activity, obstructive sleep apnea, sleep.
Abstract: Acute and sustained activation of the sympathetic nervous system are clinical hallmarks of both obstructive and central sleep apnea. Conversely, their treatment has been shown to reverse these abnormalities. The objectives of this brief review are to summarize: 1) present knowledge concerning the mechanisms, magnitude and consequences of night- and day-time sympathetic nervous system activation in patients with these sleep-related breathing disorders; and 2) the impact on the sympathetic nervous system and on blood pressure of their specific treatment.
Export Options
About this article
Cite this article as:
Floras S. John, Sympathetic Nervous System in Patients with Sleep Related Breathing Disorders, Current Hypertension Reviews 2016; 12 (1) . https://dx.doi.org/10.2174/1573402112666160114093359
DOI https://dx.doi.org/10.2174/1573402112666160114093359 |
Print ISSN 1573-4021 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6506 |
Call for Papers in Thematic Issues
Arterial Stiffness in hypertension and left ventricular dysfunction, PWV, Heart Failure
Large artery (aortic) stiffening has important consequences on cardiovascular health, including isolated systolic hypertension, excessive penetration of pulsatile energy into the microvasculature of target organs that operate at low vascular resistance, and abnormal ventricular-arterial interactions that promote left ventricular remodeling, dysfunction and failure. Large artery stiffness independently predicts cardiovascular risk ...read more
Pediatric Hypertension
Scope: This special feature focuses on the latest research and clinical advances in the field of pediatric hypertension. We welcome original research papers, review articles, case reports, as well as technical and methodological discussions from academia and clinical practitioners worldwide. Topics of interest include but are not limited to: Epidemiology ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
The Action of Polyphenols in Diabetes Mellitus and Alzheimer's Disease: A Common Agent for Overlapping Pathologies
Current Neuropharmacology Treatment of Chronic Hepatitis C Virus Using Direct Acting Antivirals in Geriatric Egyptian Patients
Recent Advances in Anti-Infective Drug Discovery Altered Calmodulin Degradation and Signaling in Non-Neuronal Cells from Alzheimer’s Disease Patients
Current Alzheimer Research Hypertensive Left Ventricular Hypertrophy Regression: Does It Matter?
Current Hypertension Reviews Lipid Lowering Agents and the Endothelium: An Update after 4 Years
Current Vascular Pharmacology Gene Therapy Strategies to Prevent Autoimmune Disorders
Current Gene Therapy Pathophysiological Roles of Nitric Oxide: In the Heart and the Coronary Vasculature
Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Diabetes
Current Pharmaceutical Design New Genetic Polymorphisms as an Epidemiological Factor of Arterial Hypertension in Patients with Hyposodical Diet
Current Hypertension Reviews Non Invasive Imaging of Myocardial Infarction with Computed Tomography and Magnetic Resonance
Current Vascular Pharmacology Mitochondrial Physiology and Toxicity (Mitotoxicity); Importance for the Immune System, Programmed Cell Death and Cancer
Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents Past, Present and Future Therapeutics for Cerebellar Ataxias
Current Neuropharmacology Endothelial Expression of MHC Class II Molecules in Autoimmune Disease
Current Pharmaceutical Design Cell Therapy for Myocardial Regeneration
Current Molecular Medicine Testosterone and Cardioprotection Against Myocardial Ischemia
Cardiovascular & Hematological Disorders-Drug Targets Pharmacogenomic Considerations in the Treatment of the Pediatric Cardiomyopathy Called Barth Syndrome
Recent Patents on Biotechnology Therapeutic Potential of Caffeic Acid Phenethyl Ester (CAPE) in Diabetes
Current Medicinal Chemistry The Fabry Cardiomyopathy - Diagnostic Approach and Current Treatment
Current Pharmaceutical Design Irbesartan: Second Generation of ARB as Metabosartan
Current Hypertension Reviews Rac-1 as a New Therapeutic Target in Cerebro- and Cardio-Vascular Diseases
Current Drug Targets