Abstract
Carbonyl chemistry, specifically aldol reactions, is one of the most efficient and elegant strategies to build carbon-carbon bonds. In the last 15 years in Brazil, our research group and others have worked on the development and application of stereoselective aldol reactions, with direct application in the asymmetric synthesis of several natural products of biological interest. In this review, we highlight the major Brazilian contributions to this field.
Keywords: Aldol Reactions, Stereoselectivity, total synthesis, natural products.
Current Organic Synthesis
Title:Exploring the Aldol Reaction in the Synthesis of Bioactive Compounds
Volume: 12 Issue: 5
Author(s): Marco A.B. Ferreira, Luiz C Dias, Ives A. Leonarczyk, Ellen C. Polo and Emílio C. de Lucca
Affiliation:
Keywords: Aldol Reactions, Stereoselectivity, total synthesis, natural products.
Abstract: Carbonyl chemistry, specifically aldol reactions, is one of the most efficient and elegant strategies to build carbon-carbon bonds. In the last 15 years in Brazil, our research group and others have worked on the development and application of stereoselective aldol reactions, with direct application in the asymmetric synthesis of several natural products of biological interest. In this review, we highlight the major Brazilian contributions to this field.
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Cite this article as:
Ferreira A.B. Marco, Dias C Luiz, Leonarczyk A. Ives, Polo C. Ellen and de Lucca C. Emílio, Exploring the Aldol Reaction in the Synthesis of Bioactive Compounds, Current Organic Synthesis 2015; 12 (5) . https://dx.doi.org/10.2174/157017941205150821124901
DOI https://dx.doi.org/10.2174/157017941205150821124901 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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