摘要
纳米技术为显著提高许多致命性疾病(包括肺结核TB)的诊断提供了巨大可能性,在健康保障方面显示出了巨大的潜力。纳米药物使现代药物养生更有效地对抗疾病(特别是肺结核),并有着长效释放,半衰期延长,靶点药物浓度提高,毒性降低,副作用减少等特征。然而,疾病的严重性强烈要求(人们)研发更好的伴随养生疗法:使用纳米微粒诊断,治疗和管理病人。这篇综述为现代肺结核养生疗法指明了一些在纳米药物领域(特别是提供优秀选择性的药物分布领域)的相关疗法。这篇综述也强调了(人们)对具有高选择性,生物相容性,生物可降解性的纳米载体的需求。
关键词: 纳米药物,肺结核,药物,药物养生疗法
Current Drug Targets
Title:Nano-Based Anti-Tubercular Drug Delivery and Therapeutic Interventions in Tuberculosis
Volume: 18 Issue: 1
Author(s): Rohit Sharma, Amanpreet Kaur, A. K. Sharma, Neeraj Dilbaghi, Anil K. Sharma
Affiliation:
关键词: 纳米药物,肺结核,药物,药物养生疗法
摘要: Nanotechnology has shown great promise in health care offering numerous possibilities to significantly improve diagnosis of many dreadful diseases including Tuberculosis (TB). Nanomedicine has made the current drug regimen more effective against diseases particularly TB with attributes like sustained release, increased half life, higher drug concentrations at target sites, reduced toxicity and lesser side effects. However because of the severity of the disease, there is a strong urge to develop better approaches with some concomitant regimens using nano-particles to diagnose, treat and manage TB patients. The current review highlights some of the evolving strategies in the field of nanomedicine particularly drug delivery offering promising alternative for the current TB regimens. The study also emphasizes upon the need to design more effective nanocarriers which are highly specific, biocompatible and biodegradable as well.
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Rohit Sharma, Amanpreet Kaur, A. K. Sharma, Neeraj Dilbaghi, Anil K. Sharma , Nano-Based Anti-Tubercular Drug Delivery and Therapeutic Interventions in Tuberculosis, Current Drug Targets 2017; 18 (1) . https://dx.doi.org/10.2174/1389450116666150804110238
DOI https://dx.doi.org/10.2174/1389450116666150804110238 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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