Abstract
Rapidly increasing number of diabetic patients across the world is a great challenge to the current therapeutic approach. Although the traditional method of rendering exogenous insulin is an established method of treatment, it is not sufficient and often causes lethal hypoglycemia. There is also a good amount of success with whole organ transplantation or Islet cells’ transplantation. But this technique is limited with regards the availability of donors. Currently, many clinicians and researchers are involved in clinical studies using various different stem cells from embryonic as well as adult sources for the treatment of diabetes. In this review we have tried to discuss the results of various clinical trials using stem cells. We have also tried to look at various stem cell types and the routes of injections that are currently being followed world wide.
Keywords: Clinical trials, diabetes, stem cells, mesenchymal stem cells.
Current Diabetes Reviews
Title:Status of Stem Cell Based Clinical Trials in the Treatment for Diabetes
Volume: 9 Issue: 6
Author(s): Chandra Viswanathan and Shabari Sarang
Affiliation:
Keywords: Clinical trials, diabetes, stem cells, mesenchymal stem cells.
Abstract: Rapidly increasing number of diabetic patients across the world is a great challenge to the current therapeutic approach. Although the traditional method of rendering exogenous insulin is an established method of treatment, it is not sufficient and often causes lethal hypoglycemia. There is also a good amount of success with whole organ transplantation or Islet cells’ transplantation. But this technique is limited with regards the availability of donors. Currently, many clinicians and researchers are involved in clinical studies using various different stem cells from embryonic as well as adult sources for the treatment of diabetes. In this review we have tried to discuss the results of various clinical trials using stem cells. We have also tried to look at various stem cell types and the routes of injections that are currently being followed world wide.
Export Options
About this article
Cite this article as:
Viswanathan Chandra and Sarang Shabari, Status of Stem Cell Based Clinical Trials in the Treatment for Diabetes, Current Diabetes Reviews 2013; 9 (6) . https://dx.doi.org/10.2174/15733998113096660082
DOI https://dx.doi.org/10.2174/15733998113096660082 |
Print ISSN 1573-3998 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6417 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Novel Indications for Benzodiazepine Antagonist Flumazenil in GABA Mediated Pathological Conditions of the Central Nervous System
Current Pharmaceutical Design Neural Stem Cell Transplantation and CNS Diseases
CNS & Neurological Disorders - Drug Targets Role of Neuromodulation and Optogenetic Manipulation in Pain Treatment
Current Neuropharmacology The Neuroprotective Effect of Ginkgo biloba Leaf Extract and its Possible Mechanism
Central Nervous System Agents in Medicinal Chemistry Introduction to Psychiatric/Psychosocial Rehabilitation (PSR): History and Foundations
Current Psychiatry Reviews Cellular Delivery In Vivo of siRNA-Based Therapeutics
Current Pharmaceutical Design The Neuroprotective Role of PEDF: Implication for the Therapy of Neurological Disorders
Current Molecular Medicine A Comprehensive Review of Alzheimer’s Association with Related Proteins: Pathological Role and Therapeutic Significance
Current Neuropharmacology Nose to Brain Delivery of Nanoformulations for Neurotherapeutics in Parkinson’s Disease: Defining the Preclinical, Clinical and Toxicity Issues
Current Drug Delivery NK-1 Receptor Antagonists: A New Generation of Anticancer Drugs
Mini-Reviews in Medicinal Chemistry Pharmacological and Biological Therapies for Metabolic Bone Disease in Critical Illness: An Integrative Physiology Approach
Current Drug Therapy Chemokine Network in the Nervous System: A New Target for Pain Relief
Current Medicinal Chemistry Editorial (Thematic Issue: Induced Cell-Based Transplantation to Therapeutically Target Spinal Cord Disorders)
Current Stem Cell Research & Therapy Gut-Brain Axis in Gastric Mucosal Damage and Protection
Current Neuropharmacology Myelin Sheaths and Autoimmune Response Induced by Myelin Proteins and Alphaviruses. I. Physicochemical Background
Current Medicinal Chemistry Regenerative Medicine in Retina: The Future Cure
Current Tissue Engineering (Discontinued) Dissecting the Therapeutic Relevance of Gene Therapy in NeuroAIDS: An Evolving Epidemic
Current Gene Therapy Cannabis sativa L. Constituents and Their Role in Neuroinflammation
Current Bioactive Compounds PPARs in Neurodegenerative and Neuroinflammatory Pathways
Current Alzheimer Research Recent Patents in Cell Therapy for Amyotrophic Lateral Sclerosis
Recent Patents on Regenerative Medicine