Abstract
A new series of gem-phosphonate-phosphates bearing N-alkyl groups and aromatic substituents has been prepared by reductive cleavage of the isoxazolidine ring with metal carbonyls, using the gem-phosphonate-phosphate rearrangement.
Keywords: Apolipoprotein E, bisphosphonates, gem-phosphonate-phosphate rearrangement, isoxazolidines, ring opening, transition-metal carbonyls.
Current Organic Synthesis
Title:Synthesis of a Novel Class of gem-Phosphonate-Phosphates by Reductive Cleavage of the Isoxazolidine Ring
Volume: 11 Issue: 3
Author(s): Olga Bortolini, Iqbal Mulani, Antonio De Nino, Loredana Maiuolo, Alessandro Melicchio, Beatrice Russo and Donatella Granchi
Affiliation:
Keywords: Apolipoprotein E, bisphosphonates, gem-phosphonate-phosphate rearrangement, isoxazolidines, ring opening, transition-metal carbonyls.
Abstract: A new series of gem-phosphonate-phosphates bearing N-alkyl groups and aromatic substituents has been prepared by reductive cleavage of the isoxazolidine ring with metal carbonyls, using the gem-phosphonate-phosphate rearrangement.
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Cite this article as:
Bortolini Olga, Mulani Iqbal, Nino De Antonio, Maiuolo Loredana, Melicchio Alessandro, Russo Beatrice and Granchi Donatella, Synthesis of a Novel Class of gem-Phosphonate-Phosphates by Reductive Cleavage of the Isoxazolidine Ring, Current Organic Synthesis 2014; 11 (3) . https://dx.doi.org/10.2174/15701794113109990061
DOI https://dx.doi.org/10.2174/15701794113109990061 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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