Generic placeholder image

Recent Patents on Endocrine, Metabolic & Immune Drug Discovery


ISSN (Print): 1872-2148
ISSN (Online): 2212-3334

Kisspeptin: Paving the Way to a New Therapeutic Avenue in Reproduction

Author(s): Channa N. Jayasena, George Tharakan and Waljit S. Dhillo

Volume 3, Issue 2, 2009

Page: [87 - 93] Pages: 7

DOI: 10.2174/187221409788452354

Price: $65


Dysfunction of the hypothalamo-pituitary gonadal (HPG) axis may result in a variety of disorders, ranging from precocious puberty to infertility. Current therapies for such disorders have varying degrees of success, and are associated with adverse effects and / or practical limitations. The recent identification of Kisspeptin as a critical regulator of reproduction, may offer a new avenue for therapeutically manipulating the HPG axis. This article provides a synopsis of the role of Kisspeptin and the Kisspeptin receptor in reproduction, with an emphasis on potential areas of its exploitation as a therapeutic or diagnostic tool. This article also reviews some of the recent patents related to the field.

Keywords: Kisspeptin, metastin, GPR54, gonadotrophin, infertility, hypothalamus, GnRH

« Previous

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy