Abstract
Over the past 20 - 30 years, there has been a tremendous increase in the number of bone replacement procedures annually, and there now have an estimated total cost of US$140 billion worldwide. The conventional engineering approach of repairing bone fracture is to implant a synthetic metallic prosthesis. However, bone healing often or sometimes fails and this result leads to substantial levels of disability and consequent long-term worldwide healthcare costs. Therefore, recently, attention has been focused on applying a bioactive coating on the surface of a prosthetic implant to enhance biocompatibility and bioactivity. This article will consider the most relevant developments in this emerging field, addressing three main coating techniques namely plasma spraying, magnetron sputtering and biomimetic deposition.
Keywords: Calcium phosphate, hydroxyapatite, silicon, spraying, sputtering, biomimetic
Recent Patents on Engineering
Title: Bioactive Medical Coatings for Bone Tissue Engineering
Volume: 1 Issue: 3
Author(s): Eng S. Thian, Jie Huang, William Bonfield and Serena M. Best
Affiliation:
Keywords: Calcium phosphate, hydroxyapatite, silicon, spraying, sputtering, biomimetic
Abstract: Over the past 20 - 30 years, there has been a tremendous increase in the number of bone replacement procedures annually, and there now have an estimated total cost of US$140 billion worldwide. The conventional engineering approach of repairing bone fracture is to implant a synthetic metallic prosthesis. However, bone healing often or sometimes fails and this result leads to substantial levels of disability and consequent long-term worldwide healthcare costs. Therefore, recently, attention has been focused on applying a bioactive coating on the surface of a prosthetic implant to enhance biocompatibility and bioactivity. This article will consider the most relevant developments in this emerging field, addressing three main coating techniques namely plasma spraying, magnetron sputtering and biomimetic deposition.
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Cite this article as:
Thian S. Eng, Huang Jie, Bonfield William and Best M. Serena, Bioactive Medical Coatings for Bone Tissue Engineering, Recent Patents on Engineering 2007; 1 (3) . https://dx.doi.org/10.2174/187221207782411638
DOI https://dx.doi.org/10.2174/187221207782411638 |
Print ISSN 1872-2121 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4047 |
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