Abstract
Complement has been long perceived as an innate immune system that plays a pivotal role in the maintenance of host defense against infectious agents and the propagation of pro-inflammatory responses in the context of human disease. Complement activation has been associated with the onset of acute inflammatory reactions leading to complications such as acute graft rejection, local tissue injury and multiorgan failure. However, recent studies have indicated that various complement activation products may exert a beneficial effect by contributing
Keywords: Immunity, proteins, multiorgan
Current Drug Targets - Inflammation & Allergy
Title: Complement: An Inflammatory Pathway Fulfilling Multiple Roles at the Interface of Innate Immunity and Development
Volume: 4 Issue: 1
Author(s): D. Mastellos, A. E. Germenis and J. D. Lambris
Affiliation:
Keywords: Immunity, proteins, multiorgan
Abstract: Complement has been long perceived as an innate immune system that plays a pivotal role in the maintenance of host defense against infectious agents and the propagation of pro-inflammatory responses in the context of human disease. Complement activation has been associated with the onset of acute inflammatory reactions leading to complications such as acute graft rejection, local tissue injury and multiorgan failure. However, recent studies have indicated that various complement activation products may exert a beneficial effect by contributing
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Cite this article as:
Mastellos D., Germenis E. A. and Lambris D. J., Complement: An Inflammatory Pathway Fulfilling Multiple Roles at the Interface of Innate Immunity and Development, Current Drug Targets - Inflammation & Allergy 2005; 4 (1) . https://dx.doi.org/10.2174/1568010053622993
DOI https://dx.doi.org/10.2174/1568010053622993 |
Print ISSN 1568-010X |
Publisher Name Bentham Science Publisher |
Online ISSN 1568-010X |
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