Abstract
Nanogels of cholesterol-bearing pullulan modified with amino-groups (CHPNH2) were utilized as a career to introduce quantum dots (QDs) into periodontal ligament (PDL) cells. Nanogel-QD effectively labeled PDL cells over 3 weeks. These results indicate that CHPNH2nanogels have a potential as a research tool in the studies of intracellular delivery system.
Keywords: Periodontal ligament cell, intracellular delivery, nanogel, quantum dot, live cell imaging
Drug Metabolism Letters
Title: Intracellular Delivery of Nanogel-Quantum Dot Hybrid Nanoparticles into Human Periodontal Ligament Cells
Volume: 1 Issue: 2
Author(s): Tomoe Fukui, Hiroaki Kobayashi, Urara Hasegawa, Toshiyuki Nagasawa, Kazunari Akiyoshi and Isao Ishikawa
Affiliation:
Keywords: Periodontal ligament cell, intracellular delivery, nanogel, quantum dot, live cell imaging
Abstract: Nanogels of cholesterol-bearing pullulan modified with amino-groups (CHPNH2) were utilized as a career to introduce quantum dots (QDs) into periodontal ligament (PDL) cells. Nanogel-QD effectively labeled PDL cells over 3 weeks. These results indicate that CHPNH2nanogels have a potential as a research tool in the studies of intracellular delivery system.
Export Options
About this article
Cite this article as:
Fukui Tomoe, Kobayashi Hiroaki, Hasegawa Urara, Nagasawa Toshiyuki, Akiyoshi Kazunari and Ishikawa Isao, Intracellular Delivery of Nanogel-Quantum Dot Hybrid Nanoparticles into Human Periodontal Ligament Cells, Drug Metabolism Letters 2007; 1 (2) . https://dx.doi.org/10.2174/187231207780363570
DOI https://dx.doi.org/10.2174/187231207780363570 |
Print ISSN 1872-3128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1874-0758 |
Related Articles
-
Identifying Biomarkers of Lung Cancer in the Post-Genomic Era
Current Pharmacogenomics Molecularly Engineered Polymer-Based Systems in Drug Delivery and Regenerative Medicine
Current Pharmaceutical Design Association of Viruses in the Development of Cardiovascular Diseases
Current Pharmaceutical Design Proresolution Mediators and Receptors: Novel Drug Targets for Enhancing Pharmacological Armamentarium against Periodontal Inflammation
Infectious Disorders - Drug Targets Novel Anti-Cancer Strategy in Bone Tumors by Targeting Molecular and Cellular Modulators of Bone Resorption
Recent Patents on Anti-Cancer Drug Discovery Enhanced Transdermal Delivery of Epidermal Growth Factor Facilitated by Dual Peptide Chaperone Motifs
Protein & Peptide Letters <I>Grewia asiatica</I> Mucilage: A Smart Gelling Polymeric Material for Pharmaceutical Applications <i>In Vitro</i> Studies
Current Materials Science Counteracting Oxidative Stress in Pregnancy through Modulation of Maternal Micronutrients and Omega-3 Fatty Acids
Current Medicinal Chemistry The Role of MAPK Signal Transduction Pathways in the Response to Oxidative Stress in the Fungal Pathogen Candida albicans: Implications in Virulence
Current Protein & Peptide Science Post Translational Modification and Its Pathologic Association in Rheumatoid Arthritis: A Brief Perspective
Current Protein & Peptide Science Microbial Polysaccharides and their Derivatives as Current and Prospective Pharmaceuticals
Current Pharmaceutical Design An update on Anti-inflammatory Compounds: A Review
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Psychiatric Rehabilitation Pertaining to Health Care Environments: Facilitating Skills and Supports of People with Mental Illness in Relation to their Mental and Physical Health Care
Current Psychiatry Reviews Editorial (Thematic Issue: Is The Female Heart Exposed To Cardiovascular Disease?)
Current Medicinal Chemistry Synthesis and Biological Activities of 2,6-Dihydroxy-4-Isopentenyloxychalcone as an Antimicrobial and Anti-Inflammatory Compound
Medicinal Chemistry Phthalocyanine-Biomolecule Conjugated Photosensitizers for Targeted Photodynamic Therapy and Imaging
Current Drug Metabolism Decoding the Link between Periodontitis and Neuroinflammation: The Journey of Bacterial Extracellular Vesicles
Current Genomics Use of Anti-Infective Drugs in Rheumatology
Anti-Infective Agents in Medicinal Chemistry Sustained Delivery of Interferons by Micro- and Nanosystems
Recent Patents on Materials Science The Role of the Osteoimmune Axis in the Inflammation of the Inner Auditory Ear and with Regard to the Putative Anticarcinogenetic Principle: Part 2
Inflammation & Allergy - Drug Targets (Discontinued)