Abstract
Duchenne muscular dystrophy is the most common form of the childhood muscular dystrophies. It follows a predictable clinical course marked by progressive skeletal muscle weakness, lost of ambulation before teen- age and death in early adulthood secondary to respiratory or cardiac failure. Becker muscular dystrophy is less common and has a milder clinical course but also results in respiratory and cardiac failure. Female carriers of both entities are also affected in a variable degree. The natural history of the cardiac involvement in these diseases has not been well established and without screening it progresses asymptomatically until the cardiac reserve has been eroded, when symptoms and signs of cardiac failure emerge. The purpose of this work is to provide recommendations for adequate cardiovascular care in this particular population based on the updated literature as referenced.
Keywords: Neuromuscular diseases, Duchenne muscular dystrophy, Becker muscular dystrophy, cardiovascular care
Current Pediatric Reviews
Title: Cardiovascular Surveillance of Duchenne and Becker Muscular Dystrophy and Female Carriers
Volume: 4 Issue: 3
Author(s): Virginia Spehrs-Ciaffi, Pierre-Yves Jeannet and Nicole Sekarski
Affiliation:
Keywords: Neuromuscular diseases, Duchenne muscular dystrophy, Becker muscular dystrophy, cardiovascular care
Abstract: Duchenne muscular dystrophy is the most common form of the childhood muscular dystrophies. It follows a predictable clinical course marked by progressive skeletal muscle weakness, lost of ambulation before teen- age and death in early adulthood secondary to respiratory or cardiac failure. Becker muscular dystrophy is less common and has a milder clinical course but also results in respiratory and cardiac failure. Female carriers of both entities are also affected in a variable degree. The natural history of the cardiac involvement in these diseases has not been well established and without screening it progresses asymptomatically until the cardiac reserve has been eroded, when symptoms and signs of cardiac failure emerge. The purpose of this work is to provide recommendations for adequate cardiovascular care in this particular population based on the updated literature as referenced.
Export Options
About this article
Cite this article as:
Spehrs-Ciaffi Virginia, Jeannet Pierre-Yves and Sekarski Nicole, Cardiovascular Surveillance of Duchenne and Becker Muscular Dystrophy and Female Carriers, Current Pediatric Reviews 2008; 4 (3) . https://dx.doi.org/10.2174/157339608785856027
DOI https://dx.doi.org/10.2174/157339608785856027 |
Print ISSN 1573-3963 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6336 |
![Wayfinder Image](/images/wayfinder.jpg)
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Recent Patents on Polymeric Scaffolds for Tissue Engineering
Recent Patents on Biomedical Engineering (Discontinued) Therapeutic Potential of Cannabinoids in the Treatment of Neuroinflammation Associated with Parkinsons Disease
Mini-Reviews in Medicinal Chemistry Doxorubicin-induced Cardiotoxicity and Cardioprotective Agents: Classic and New Players in the Game
Current Pharmaceutical Design SynB3 Conjugated QBP1 Passes Blood-Brain Barrier Models and Inhibits PolyQ Protein Aggregation
Protein & Peptide Letters Parathyroid Hormone and Heart Failure: Novel Biomarker Strategy
Endocrine, Metabolic & Immune Disorders - Drug Targets Editorial[Hot Topic:Stem Cell Therapy for Cardiovascular Diseases:Are We Still at the Beginning of A Long Road?(Guest Editor:Lino M Goncalves)
Cardiovascular & Hematological Disorders-Drug Targets Neuroprotection by Resveratrol in Diabetic Neuropathy: Concepts & Mechanisms
Current Medicinal Chemistry Energy Remodeling, Mitochondrial Disorder and Heart Failure
Current Pharmaceutical Design Hypertension in Type 2 Diabetes Mellitus: Do We Need to Redefine the Role of Sulfonylureas?
Recent Advances in Cardiovascular Drug Discovery (Discontinued) The Long Way to Objectify Organ Damage Related to Cocaine Abuse: Oxidative Stress is the Main Culprit
Mini-Reviews in Organic Chemistry Adult Stem Cells and Biocompatible Scaffolds as Smart Drug Delivery Tools for Cardiac Tissue Repair
Current Medicinal Chemistry Characterization of Supraventricular Tachycardia in Infants: Clinical and Instrumental Diagnosis
Current Pharmaceutical Design T1 Mapping and Amide Proton Transfer Weighted Imaging for Predicting Lymph Node Metastasis in Patients with Rectal Cancer
Current Medical Imaging Multimodality Imaging in Cardiac Sarcoidosis: Is There a Winner?
Current Cardiology Reviews Hypoxia and Fetal Heart Development
Current Molecular Medicine Antibodies Against G-Protein Coupled Receptors: Novel Uses in Screening and Drug Development
Combinatorial Chemistry & High Throughput Screening Promises of Lipid-based Drug Delivery Systems in the Management of Breast Cancer
Current Pharmaceutical Design Targeting Mitochondrial Dysfunction in Chronic Heart Failure: Current Evidence and Potential Approaches
Current Pharmaceutical Design Molecular Genetics of Left Ventricular Dysfunction
Current Molecular Medicine Sex Differences in Biomarkers for Predicting Cardiovascular and Coronary Events
Current Vascular Pharmacology