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Abstract
The endogenous canabinoid system (ECS) is involved in the regulation of an important number of central and peripheral physiological effects. Among all these functions, the control of the cellular proliferation has become a focus of major attention as opening new therapeutic possibilities for the use of cannabinoids as potential antitumor agents. The capacity of endogenous and synthetic cannabinoids to induce apoptosis of different tumoral cells in culture and in vivo, the mechanism underlying and the potential therapeutic applications are discussed in this review.
Keywords: endogenous cannabinoid system, cellular proliferation, antitumoral properties of cannabinoids, tumoral cells, cancer
Mini-Reviews in Medicinal Chemistry
Title: Involvement of Cannabinoids in Cellular Proliferation
Volume: 5 Issue: 1
Author(s): Maria L. Lopez-Rodriguez, Alma Viso, Silvia Ortega-Gutierrez and Ines Diaz-Laviadac
Affiliation:
Keywords: endogenous cannabinoid system, cellular proliferation, antitumoral properties of cannabinoids, tumoral cells, cancer
Abstract: The endogenous canabinoid system (ECS) is involved in the regulation of an important number of central and peripheral physiological effects. Among all these functions, the control of the cellular proliferation has become a focus of major attention as opening new therapeutic possibilities for the use of cannabinoids as potential antitumor agents. The capacity of endogenous and synthetic cannabinoids to induce apoptosis of different tumoral cells in culture and in vivo, the mechanism underlying and the potential therapeutic applications are discussed in this review.
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Cite this article as:
Lopez-Rodriguez L. Maria, Viso Alma, Ortega-Gutierrez Silvia and Diaz-Laviadac Ines, Involvement of Cannabinoids in Cellular Proliferation, Mini-Reviews in Medicinal Chemistry 2005; 5 (1) . https://dx.doi.org/10.2174/1389557053402819
DOI https://dx.doi.org/10.2174/1389557053402819 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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