Abstract
General anesthetic drugs interact with many receptors in the nervous system, but only a handful of these interactions are critical for producing anesthesia. Over the last 20 years, neuropharmacologists have revealed that one of the most important target sites for general anesthetics is the GABAA receptor. In this review we will discuss what is known about anesthetic – GABAA receptor interactions.
Keywords: GABAA Receptor, General Anesthetic, Isoflurane, Desflurane, Sevoflurane, Propofol, Etomidate, Barbiturates
Current Neuropharmacology
Title: General Anesthetic Actions on GABAA Receptors
Volume: 8 Issue: 1
Author(s): Paul S. Garcia, Scott E. Kolesky and Andrew Jenkins
Affiliation:
Keywords: GABAA Receptor, General Anesthetic, Isoflurane, Desflurane, Sevoflurane, Propofol, Etomidate, Barbiturates
Abstract: General anesthetic drugs interact with many receptors in the nervous system, but only a handful of these interactions are critical for producing anesthesia. Over the last 20 years, neuropharmacologists have revealed that one of the most important target sites for general anesthetics is the GABAA receptor. In this review we will discuss what is known about anesthetic – GABAA receptor interactions.
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Cite this article as:
Garcia S. Paul, Kolesky E. Scott and Jenkins Andrew, General Anesthetic Actions on GABAA Receptors, Current Neuropharmacology 2010; 8 (1) . https://dx.doi.org/10.2174/157015910790909502
DOI https://dx.doi.org/10.2174/157015910790909502 |
Print ISSN 1570-159X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6190 |
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