Polyhydroxylated Carbobicyclic Sugar Mimics. Part 2. The Chiron Approach to Bicyclic Systems

The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more

Carbohydrates are one of the most abundant natural products and are considered to be extremely important biomolecules for their ever-increasing impact on chemistry and biology. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell ...read more

Electrochemistry based point of care diagnostics is a powerful tool which can revolutionize the current concept of personalize health care industry. There have been several efforts to amalgamate cutting edge technologies (nanotechnology, surface technology, anti-biofouling strategies) while developing assays. The success of each electrochemical sensor is very dependable upon how ...read more

Conventional methods for carrying out carbon–X bond formation are typically conducted at harsh reaction conditions, and rely on expensive catalysts as well as the use of stoichiometric, and perhaps toxic, oxidants. In this regard, electrochemical synthesis has recently been recognized as a sustainable and scalable strategy for the construction of ...read more