Abstract
Wikstroemia indica (L.) C. A. Mey. is a member of family Thymelaeaceae and mainly distributes in middle and southeast part of China. As a traditional Chinese herb, this plant has long been employed as antipyretics, detoxicants, expectorants, vermifuges as well as aborticides in clinic practice. However, its use has mainly been based on empirical findings during hundreds and thousands of years. Recent studies indicated that W. indica contains abundant bioactive components including flavonoids, biflavonoids, coumarins, lignans, volatile oils, polysaccharides etc. This paper provides a comprehensive review of pharmacological relevant compounds of W. indica that have been characterized to date, and introduces the research progresses supporting its pharmacological action and clinical application. Particular attention has been given to antibacterial, antiviral, anti-inflammatory, anti-tumor and antifertility effects. Some examples of clinical applications of prepared W. indica in treatment of various diseases are outlined. Finally, the trend and necessity of future research, such as quantification of individual constituents extracted from W. indica and the assessment of their pharmacological activities in human body are proposed.
Keywords: Wikstroemia indica, bioactive components, pharmacological action, clinical application
Current Pharmaceutical Biotechnology
Title: Bioactive Components and Pharmacological Action of Wikstroemia indica (L.) C. A. Mey and Its Clinical Application
Volume: 10 Issue: 8
Author(s): Yan-Min Li, Liang Zhu, Jian-Guo Jiang, Li Yang and Ding-Yong Wang
Affiliation:
Keywords: Wikstroemia indica, bioactive components, pharmacological action, clinical application
Abstract: Wikstroemia indica (L.) C. A. Mey. is a member of family Thymelaeaceae and mainly distributes in middle and southeast part of China. As a traditional Chinese herb, this plant has long been employed as antipyretics, detoxicants, expectorants, vermifuges as well as aborticides in clinic practice. However, its use has mainly been based on empirical findings during hundreds and thousands of years. Recent studies indicated that W. indica contains abundant bioactive components including flavonoids, biflavonoids, coumarins, lignans, volatile oils, polysaccharides etc. This paper provides a comprehensive review of pharmacological relevant compounds of W. indica that have been characterized to date, and introduces the research progresses supporting its pharmacological action and clinical application. Particular attention has been given to antibacterial, antiviral, anti-inflammatory, anti-tumor and antifertility effects. Some examples of clinical applications of prepared W. indica in treatment of various diseases are outlined. Finally, the trend and necessity of future research, such as quantification of individual constituents extracted from W. indica and the assessment of their pharmacological activities in human body are proposed.
Export Options
About this article
Cite this article as:
Li Yan-Min, Zhu Liang, Jiang Jian-Guo, Yang Li and Wang Ding-Yong, Bioactive Components and Pharmacological Action of Wikstroemia indica (L.) C. A. Mey and Its Clinical Application, Current Pharmaceutical Biotechnology 2009; 10 (8) . https://dx.doi.org/10.2174/138920109789978748
DOI https://dx.doi.org/10.2174/138920109789978748 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
Call for Papers in Thematic Issues
Artificial Intelligence in Bioinformatics
Bioinformatics is an interdisciplinary field that analyzes and explores biological data. This field combines biology and information system. Artificial Intelligence (AI) has attracted great attention as it tries to replicate human intelligence. It has become common technology for analyzing and solving complex data and problems and encompasses sub-fields of machine ...read more
Latest Advancements in Biotherapeutics
The scope of this thematic issue is to comprehensively explore the rapidly evolving landscape of biotherapeutics, emphasizing breakthroughs in precision medicine. Encompassing diverse therapeutic modalities, the issue will delve into the latest developments in monoclonal antibodies, CRISPR/Cas gene editing, CAR-T cell therapies, and innovative drug delivery systems, such as nanoparticle-based ...read more
![](/images/wayfinder.jpg)
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Role of Copper in Angiogenesis and Its Medicinal Implications
Current Medicinal Chemistry Effects of Dietary Polyunsaturated Fatty Acids on Mitochondria
Current Pharmaceutical Design Patents and Heart Valve Surgery - II: Tissue Valves
Recent Patents on Cardiovascular Drug Discovery High Throughput Metabolomics in Clinical Studies: Review and New Applications to Remote Ischemic Preconditioning
Current Topics in Medicinal Chemistry Mental Health Disorder Therapeutic Modalities Modified for the GMS
Current Psychiatry Reviews Physical Activity: Do Patients Infected with HIV Practice? How Much? A Systematic Review
Current HIV Research TRP Channels in Vascular Disorders
Current Topics in Medicinal Chemistry Redefining the Role of Long-Acting Phosphodiesterase Inhibitor Tadalafil in the Treatment of Diabetic Erectile Dysfunction
Current Diabetes Reviews RAGE in Diabetic Nephropathy
Current Molecular Medicine The Complex Link Between Schizophrenia and Dementia: Targeting Ca2+/cAMP Signalling
Current Pharmaceutical Design Cardiovascular cGMP-Generating Systems in Physiological and Pathological Conditions
Current Medicinal Chemistry Mitochondrial Dynamics: An Emerging Paradigm in Ischemia-Reperfusion Injury
Current Pharmaceutical Design Let Them Eat Cake
Current Nutrition & Food Science Emerging Perspectives on DNA Double-strand Breaks in Neurodegenerative Diseases
Current Neuropharmacology Investigating Physical, Psychological and Social Well-being of Older Persons in Jordan
Current Aging Science Boswellic Acids: A Critical Appraisal of Their Therapeutic and Nutritional Benefits in Chronic Inflammatory Diseases
Endocrine, Metabolic & Immune Disorders - Drug Targets Vascular Effects of Estrogenic Menopausal Hormone Therapy
Reviews on Recent Clinical Trials Pharmacological and Clinical Applications of Natriuretic Peptides: Accepted Knowledges or Changing Views?
Current Pharmaceutical Analysis Dyspnea in Cancer Patients: A Well-Known and Neglected Symptom
Reviews on Recent Clinical Trials Obstructive Sleep Apnea in Chronic Obstructive Pulmonary Disease: The Overlap Syndrome
Current Respiratory Medicine Reviews