Liposomal Drug Delivery: Progress, Clinical Outlook, and Ongoing Challenges

Title:Liposomal Drug Delivery: Progress, Clinical Outlook, and Ongoing Challenges

Volume: 18 Issue: 3

Author(s): Chanchal Tiwari, Jigyasa Tomer and Dharmendra Kumar*

Affiliation:

• Department of Pharmacy, IEC College of Eng & Tech, Gautam Buddha Nagar, Uttar Pradesh, 201310, India

Keywords: Liposomal drug delivery system, liposomes, liposomal technology, advanced liposomes, pilosomes, nucleic acid drugs.

Abstract: The liposomal drug delivery system is considered an advanced drug delivery technology for formulating lipid core nano-structured particles using lipids from natural and synthetic sources. Liposomes play a wide role in improving drugs with less solubility and greater toxicity profile. Liposomes have numerous advantages, such as enhanced drug loading, good biocompatibility, prolonged drug release profile, and better pharmacokinetic properties. Numerous attempts have been made in this field in the last few years, and lots of liposomal formulations are currently being sold all over the world, and few are under clinical study. Liposomal delivery technology improves the challenges of encapsulating poor soluble drugs and maintains the stability of the formulation, along with improving the challenges of in-vivo outcomes of liposomes. The present review discussed the brief outline of the liposome drug delivery system, the innovations in the clinical application, and the significant challenges in liposomal technology.

Cite this article as:

Tiwari Chanchal, Tomer Jigyasa and Kumar Dharmendra*, Liposomal Drug Delivery: Progress, Clinical Outlook, and Ongoing Challenges, Recent Advances in Drug Delivery and Formulation 2024; 18 (3) . https://dx.doi.org/10.2174/0126673878300031240703070511