Abstract
DABCO is one of the more effective basic organocatalysts/reagents that can be used for a range of organic transformations, including C-H functionalization, formation of hetero-hetero bonds, rearrangements, the synthesis of heterocyclic compounds, cyclizations and annulations, other miscellaneous reactions. This quinquennial review aims to critically and perceptively address noteworthy contributions of non chiral catalyst DABCO for regular organic transformations from 2019 onward. The key areas of attention were the advantages and limits of the approach, in addition to the mechanistic pathway, which is required for a specific organic transformation to be performed effectively.
Keywords: DABCO, base, organocatalyst, catalysis, organic synthesis, C-H functionalization, heterocyclic ring formation, cyclization.
Current Organic Chemistry
Title:1,4-Diazabicyclo[2.2.2]octane (DABCO) in Organic Synthesis and Catalysis: A Quinquennial Report (2019-to date)
Volume: 28 Issue: 17
Author(s): Ravi Varala*, Vittal Seema, Mohammed Mujahid Alam*, Mohammed Amanullah and Beda Durga Prasad
Affiliation:
- Scrips Pharma, Mallapur, Hyderabad 500076, Telangana, India
- Research Fellow, INTI International University, Nilai, Malaysia
- Department of Chemistry, College of Science, King Khalid University, Abha, Saudi Arabia
Keywords: DABCO, base, organocatalyst, catalysis, organic synthesis, C-H functionalization, heterocyclic ring formation, cyclization.
Abstract: DABCO is one of the more effective basic organocatalysts/reagents that can be used for a range of organic transformations, including C-H functionalization, formation of hetero-hetero bonds, rearrangements, the synthesis of heterocyclic compounds, cyclizations and annulations, other miscellaneous reactions. This quinquennial review aims to critically and perceptively address noteworthy contributions of non chiral catalyst DABCO for regular organic transformations from 2019 onward. The key areas of attention were the advantages and limits of the approach, in addition to the mechanistic pathway, which is required for a specific organic transformation to be performed effectively.
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Cite this article as:
Varala Ravi*, Seema Vittal, Alam Mujahid Mohammed*, Amanullah Mohammed and Prasad Durga Beda, 1,4-Diazabicyclo[2.2.2]octane (DABCO) in Organic Synthesis and Catalysis: A Quinquennial Report (2019-to date), Current Organic Chemistry 2024; 28 (17) . https://dx.doi.org/10.2174/0113852728313865240528073519
DOI https://dx.doi.org/10.2174/0113852728313865240528073519 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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