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Current Pharmaceutical Analysis

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ISSN (Print): 1573-4129
ISSN (Online): 1875-676X

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Mini-Review Article

A Review on Working Principle and Advanced Applications of Fluorescence activated Cell Sorting Machine (FACS)

Author(s): Gurisha Garg, Preeti Patel, Ghanshyam Das Gupta and Balak Das Kurmi*

Volume 20, Issue 2, 2024

Published on: 12 March, 2024

Page: [85 - 97] Pages: 13

DOI: 10.2174/0115734129301463240306064929

Abstract

Various technologies, like flow cytometry and cell sorting, have been established in fields of biomedical research. Fluorescence-activated cell sorting is one of the most powerful techniques to witness advancement in these years. This article aims to provide an in-depth overview of the FACS applications, along with regulatory considerations and qualification parameters for the instrument. Moreover, specifications of instruments from different brands with specialized features are mentioned. FACS is a cornerstone in clinical diagnostics. This review highlights the current advancements and versatility of this indispensable technology, and the said information would be a focal paradigm for the upcoming biomedical and pharmaceutical research.

Keywords: FACS, cell sorting, flow cytometry, S3e cell sorter, qualification, enzymes.

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Graphical Abstract

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