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Current Topics in Medicinal Chemistry

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ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

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Review Article

Ginsenoside Rg3: A Review of its Anticancer Mechanisms and Potential Therapeutic Applications

Author(s): Lei Wu, Lin Bai, Wenshu Dai, Yaping Wu, Pengjun Xi, Jie Zhang and Lily Zheng*

Volume 24, Issue 10, 2024

Published on: 04 March, 2024

Page: [869 - 884] Pages: 16

DOI: 10.2174/0115680266283661240226052054

Price: $65

Abstract

Background: Traditional Chinese Medicine (TCM) has a long history of treating various diseases and is increasingly being recognized as a complementary therapy for cancer. A promising natural compound extracted from the Chinese herb ginseng is ginsenoside Rg3, which has demonstrated significant anticancer effects. It has been tested in a variety of cancers and tumors and has proven to be effective in suppressing cancer.

Objectives: This work covers various aspects of the role of ginsenoside Rg3 in cancer treatment, including its biological functions, key pathways, epigenetics, and potential for combination therapies, all of which have been extensively researched and elucidated. The study aims to provide a reference for future research on ginsenoside Rg3 as an anticancer agent and a support for the potential application of ginsenoside Rg3 in cancer treatment.

Keywords: Ginsenoside Rg3, Anticancer, Important cellular functions, Epigenetic pathways, Important pathways, Combination therapies.

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