Title:lkGraphene Nano-Derivatives in Pharmaceuticals and Biomedical Advancements: A Comprehensive Review
Volume: 9
Author(s): Yogesh Kumar, Astha Sharma, Prachi Varshney, Devdhar Yadav, Amit singh*, Naga Rani Kagithala, Pramod Sharma, Omji Porwal, Neeraj Kumar, Pradeep Kumar Sharma, Ashok Kumar Gupta and Koteswara Rao G
Affiliation:
- Department of Pharmacy, Galgotias University, Greater Noida, Uttar Pradesh, 201310, India
Keywords:
Graphene, Pharmaceutical application, Drug delivery, Cancer diagnosis, Gene delivery, Antibacterial activity, Biosensing.
Abstract: The two-dimensional structure of graphene has a flat single layer of carbon molecules
having a honeycomb crystal lattice configuration. Graphene possesses typical physicochemical
characteristics such as elevated conductivity, wide-ranging surface area, good biocompatibility,
and excellent mechanical properties. Due to their exceptional properties, graphene derivatives have
significant implementations in many fields like electronics, environmental, chemical, pharmaceutical,
and others. With its distinctive formation and biological characteristics, pharmaceutical and
biomedical applications of graphene have gained the impressive interest of researchers and scientists
over the past few years. The exceptional properties of graphene, such as its larger surface area,
which is four times greater than other nanoparticles, represented it as a prior choice for drug delivery.
Graphene derivatives are monolayer graphene, bilayer graphene, reduced Graphene Oxide
(rGO), and Graphene Oxide (GO). This review focused on different pharmaceutical applications
and the part of the progress made by different researchers on graphene and its derivatives in the
distinct field of interest, like in the delivery of drugs, cancer therapy, gene delivery, antibacterial
effect, biosensing, bioimaging, tissue engineering, and others.
