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Pharmaceutical Nanotechnology

Editor-in-Chief

ISSN (Print): 2211-7385
ISSN (Online): 2211-7393

Mini-Review Article

Decoding Therapeutic Applications of Quercetin: Recent Advancements in Nanotechnological Strategies

In Press, (this is not the final "Version of Record"). Available online 17 January, 2024
Author(s): Sonam Grewal, Neha Tiwary, Gaurav Malik, Madhukar Garg, Geeta Deswal, Bhawna Chopra, Ajmer Singh Grewal*, Ashwani K. Dhingra and Kumar Guarve
Published on: 17 January, 2024

DOI: 10.2174/0122117385271262231114075737

Price: $95

Abstract

For centuries, people have used herbal medicine to treat a diversity of health complications and as a natural substance, they have a favourable effect on our health. Herbal ingredients can be utilized as lead molecules in the innovation and development of a new drug. Flavonoids are a class of chemical compounds with diverse phenolic structures, and they are found in a wide variety of foods, including fruits, vegetables, cereals, bark, roots, stems, flowers, tea, and wine. Quercetin is the most prevalent polyphenolic bioflavonoid or flavonoid. Quercetin is found in many food products and has demonstrated a wide range of pharmacological activities, including the treatment of allergies, ocular diseases, metabolic ailments, inflammatory illnesses, cardiovascular ailments and arthritis. Quercetin has attracted interest as an emerging pharmacophore with the potential to significantly advance research and the development of novel therapeutic medicines for a variety of diseases. Despite having a huge therapeutic potential, these flavonoids have unfavourable pharmacokinetic characteristics, low bioavailability, and poor solubility, limiting their application in therapeutics. The objective of the current study is to present a new update on the major therapeutic uses of quercetin and other types of nanocarriers that contain quercetin to treat various ailments.

Keywords: Quercetin, therapeutic, drug delivery, nanomedicine, nanotechnology, flavonols, natural compounds


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