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Current Topics in Medicinal Chemistry

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ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

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Review Article

Natural Products and Biological Activities of Plants from Genus Morus: 2011-2023

Author(s): Yan-Ao Wang, Chao Liu, Xu Guo, Meng-Qi Zhang, Shutao Sun, Jin-Yue Sun, Afsar Khan*, Lu Liu* and Ying-Ying Chen*

Volume 23, Issue 28, 2023

Published on: 05 October, 2023

Page: [2640 - 2698] Pages: 59

DOI: 10.2174/0115680266257370230920055003

Price: $65

Abstract

Species of genus Morus (family Moraceae) have been used as traditional medicinal and edible resources since ancient times. Genus Morus has been acknowledged as a promising resource for the exploration of novel compounds with various bioactivities. Phytochemical investigations of the genus have led to the discovery of more than approximately 453 natural products from 2011 to 2023, mainly including flavonoids, Diels-Alder adducts, 2-arylbenzfuran, alkaloids and stilbenes. Bioactive constituents and extracts of this genus displayed a wide range of impressive biological properties including antidiabetic, anti-inflammatory, antioxidant, anti-cancer, hepatoprotective, renoprotective, and some other activities. Herein, the research progress of this genus Morus from 2011 to 2023 on phytochemistry and pharmacology are systematically presented and discussed for the first time. This current review provides the easiest access to the information on genus Morus for readers and researchers in view of enhancing the continuity on research done on this genus.

Keywords: Genus Morus, Traditional uses, Phytochemistry, Pharmacology, Prenylated flavonoids, Diels-alder adducts.

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