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摘要
对于胰腺癌的治疗有很大的未满足的需求。许多患者在确诊后都活不过5年。治疗的效果因病人而异,许多人太虚弱,无法忍受化疗或手术。不幸的是,当患者接受诊断时,肿瘤通常已经扩散,使得这些化疗无效。有效的抗癌药物可以在纳米技术的帮助下更好地配方,纳米技术可以帮助它们克服其物理化学特性的问题,例如它们的水溶性差或给药后在血液中的半衰期短。许多报道的纳米技术提供了多功能的品质,包括图像引导和控制释放,除了针对作用部位的特定位点靶向。在这篇综述中,我们将研究目前最有前途的治疗胰腺癌的纳米技术的现状,包括那些仍处于研究和开发阶段的技术,以及那些最近被给予绿色信号用于临床实践的技术。
关键词: 胰腺癌,肿瘤微环境,化疗,放疗,光动力治疗,免疫治疗,纳米技术。
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