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Combinatorial Chemistry & High Throughput Screening

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ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

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Mini-Review Article

Effect of the Application of Exosome on Gastric Cancer

Author(s): Jing Peng, Yiwen Wu, Sijun Deng, Pu Cao, Wei Yang, Tingyi Gong, Xiaoyong Lei and Xiaoyan Yang*

Volume 26, Issue 13, 2023

Published on: 22 March, 2023

Page: [2267 - 2279] Pages: 13

DOI: 10.2174/1386207326666230213141627

Price: $65

Abstract

Gastric cancer is one of the most common and highest mortality rate cancers in the world. Exosomes are vesicles secreted by cells carrying different types of molecules, such as protein and RNA. Numerous studies have confirmed that exosomes are involved in various stages of the occurrence and development of gastric cancer and play an important role. With the gradual development, exosomes have been widely employed in the diagnosis and treatment of gastric cancer. In this review, we have provided a basic overview of exosome, and discussed the role of exosome in the occurrence, proliferation, invasion, metastasis, and drug resistance in gastric cancer. In addition, we have emphasized the bright development prospect of exosome in the diagnosis and treatment of gastric cancer. The data on the discovery, diagnosis, treatment, and prognosis of gastric cancer are not particularly optimistic, but the discovery of exosome, applied in diagnosis and treatment, provides a new and effective way to improve the survival rate of patients with gastric cancer.

Keywords: Exosome, gastric cancer, diagnosis, treatment, prognosis, physiological function.

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