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Mini-Reviews in Organic Chemistry

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ISSN (Online): 1875-6298

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Mini-Review Article

Synthesis and Biological Activities of Heterocyclic Hybrids Containing Piperidine and Pyridine Moieties: Recent Developments

Author(s): Gangotri Pemawat*, Ayushi Bhatnagar and Rama Kanwar Khangarot

Volume 21, Issue 3, 2024

Published on: 04 April, 2023

Page: [346 - 369] Pages: 24

DOI: 10.2174/1570193X20666230213123453

Price: $65

Abstract

Piperidine and pyridine nuclei are essential heterocyclic systems and act as an essential underpinning for agriculture, medicines, industries, etc. The development of novel methods for the synthesis of these exemplary heterocyclic compounds and their respective hybrids, which show a wide range of biological activities, is a very fascinating theme. The derivatives of these pervasive nuclei are used as antibacterial, antimicrobial, antifungal, antimalarial, anticancer, antiproliferative, antihypertensive, antiparasitic, and many other agents. The hybrids of these nuclei have retained a distinct position in medicinal chemistry and are often incorporated in synthetic drug discovery. In this review, we have compiled relevant literature on different derivatives of piperidine and pyridine moieties and their biological activities.

Keywords: Heterocyclic, piperidine, pyridine, synthetic drug discovery, pyridine moieties, cyclic compounds.

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Graphical Abstract

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