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Current Organic Synthesis

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Review Article

Imidazole and Derivatives Drugs Synthesis: A Review

Author(s): Nidhi Rani*, Randhir Singh and Praveen Kumar

Volume 20, Issue 6, 2023

Published on: 13 January, 2023

Page: [630 - 662] Pages: 33

DOI: 10.2174/1570179420666221118100525

Price: $65

Abstract

Imidazoles have long held a special place in heterocyclic chemistry, and their derivatives have piqued interest in recent years due to their diverse chemistry and pharmacology features. Imidazole is a biologically and pharmaceutically important nitrogen-containing heterocyclic ring. As a result, researchers have been interested in imidazole molecules. For a century and a half, purine, histamine, and other natural compounds all contained the imidazole ring. A number of imidazole drugs have been prepared and marketed for the treatment of various diseases. In view of this, we herein report a detailed account of synthetic procedures for various imidazole drugs.

Keywords: Azole, marketed drugs, imidazole drugs, imidazole, drugs synthesis, derivatives drugs.

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