![conference banner](/images/conference-banner.jpeg)
Abstract
Background: Currently, studies are underway to determine whether coronary stent implantation with percutaneous transluminal coronary angioplasty before a coronary artery bypass graft (CABG) influences the prognosis of surgery. This study aimed to assess the need for future revascularisation or all-cause mortality as a composite endpoint after CABG surgery among patients with previous stent implantation.
Methods: A retrospective, non-randomised study was performed on 721 patients who underwent CABGin our centre between 2012 and 2017. This single-centre study compared two groups: 1) the previous stent group, patients with previous stent implantation (n=144), and 2) the non-previous stent group, patients without previous stent implantation (n=577).
Results: After a median follow-up of 36 months, the previous stent group presented a decreased combined event-free survival at 1, 3 and 5 years compared with the non-previous stent group (67.4, 43.5 and 23.0% vs. 91.0, 80.3 and 63.0%, respectively; p<0.01). There was also higher mortality in the previous stent group than in the non-previous stent group (96.1, 90.5 and 79.4 vs. 91.9, 75.9 and 51.0, respectively; p=0.01). The multivariable analysis of demographics, baseline comorbidity and surgical data showed previous stent implantation as an independent predictor of the composite endpoint (Hazard Ratio=3.00 and 95% confident interval=2.09-4.32; p<0.01).
Conclusion: Patients with percutaneous coronary intervention before CABG present higher comorbidities and clinical events during follow-up than those who do not undergo stenting.
Keywords: Coronary artery disease, coronary artery bypass graft, revascularisation, stent implantation, survival analysis, percutaneous coronary intervention.
[http://dx.doi.org/10.1016/j.recesp.2013.01.019] [PMID: 24776050]
[http://dx.doi.org/10.1053/j.semtcvs.2019.09.009] [PMID: 31557513]
[http://dx.doi.org/10.1093/ejcts/ezr210] [PMID: 22219477]
[http://dx.doi.org/10.1093/eurheartj/ehl001] [PMID: 16735367]
[http://dx.doi.org/10.1093/eurheartj/eht296] [PMID: 23996286]
[http://dx.doi.org/10.1093/eurheartj/ehi249] [PMID: 15824076]
[http://dx.doi.org/10.1055/s-0037-1618575] [PMID: 29351697]
[http://dx.doi.org/10.1016/j.amjcard.2005.09.064] [PMID: 16399095]
[http://dx.doi.org/10.1016/j.jtcvs.2015.01.051] [PMID: 25772280]
[http://dx.doi.org/10.1016/j.jtcvs.2008.09.005] [PMID: 19327506]
[http://dx.doi.org/10.1016/j.jtcvs.2009.03.004] [PMID: 19619774]
[http://dx.doi.org/10.1093/eurheartj/ehn026] [PMID: 18285358]
[http://dx.doi.org/10.1093/icvts/ivu449] [PMID: 25583647]
[http://dx.doi.org/10.1016/j.athoracsur.2014.12.073] [PMID: 25865763]
[http://dx.doi.org/10.1016/j.hlc.2013.04.110] [PMID: 23683716]
[http://dx.doi.org/10.1161/CIRCULATIONAHA.112.096438] [PMID: 22723305]
[http://dx.doi.org/10.1016/j.jbiomech.2007.12.005] [PMID: 18215394]
[http://dx.doi.org/10.1016/S0003-4975(03)00872-5] [PMID: 14602281]
[http://dx.doi.org/10.1093/cvr/cvt090] [PMID: 23592806]
[http://dx.doi.org/10.1161/JAHA.118.010089] [PMID: 30371287]
[http://dx.doi.org/10.1016/j.jtcvs.2011.04.018] [PMID: 21763871]
[http://dx.doi.org/10.1016/S0002-9149(83)80003-4] [PMID: 6600367]
[http://dx.doi.org/10.1016/j.jtcvs.2004.12.034] [PMID: 15942568]
[http://dx.doi.org/10.1016/j.jtcvs.2010.07.094] [PMID: 21168023]
[http://dx.doi.org/10.1161/CIRCULATIONAHA.108.842005] [PMID: 19752389]
[http://dx.doi.org/10.1016/S0735-1097(01)01806-X] [PMID: 11849852]
![Wayfinder Image](/images/wayfinder.jpg)