Login Register Cart 0
Generic placeholder image

Cardiovascular & Hematological Disorders-Drug Targets

Editor-in-Chief

ISSN (Print): 1871-529X
ISSN (Online): 2212-4063

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Research Article

Quality of Life and Depression Assessment in Patients with Acute Coronary Syndrome: A Cross-Sectional Study

Author(s): Treesa P. Varghese* and P. R Anand Vijaya Kumar

Volume 22, Issue 3, 2022

Published on: 30 September, 2022

Page: [155 - 161] Pages: 7

DOI: 10.2174/1871529X22666220830093651

Price: $65

conference banner
Abstract

Purpose: Acute Coronary Syndrome (ACS) is currently the leading cause of death in industrialized countries. Morbidity after ACS includes physical and mental disorders affecting the patient’s whole life situation and Quality of Life (QoL). The main aim of the study was to assess QoL and depression among post-ACS patients.

Methods: This was a cross-sectional observational study. A total of 112 patients who fulfilled the inclusion criteria were included in this study. A semi-structured questionnaire was administered to the patients to collect data from the patients. In this study, men and women aged 18 - 80 with ACS; patients diagnosed with Non-ST Segment Elevated Myocardial Infarction (NSTEMI) or STEMI or Angina Pectoris were included. Patients with severe mental, and physical illness and dementia were excluded from the study. QoL and depression assessment was done by RAND 36-Item Health Survey and Hamilton Depression Rating scale, respectively.

Results: Among 112 post-ACS patients, 78 patients were males, and 38 patients were females. The mean age of the study population was 64.25 ± 9.029 and with most individuals in the category of 61 -70 years. The majority of study populations were married (71.5%) and lived with their families (92.9%). In this study group, 42.9 % of the population reported at least high school education (SSLC) and 54.5% were full-time employees. Most of the patients (91.1%) were taking the medication regularly, while 55.4% of patients reported regular compliance with the follow-up. This study identified that, among various factors, older age, female gender, lower income, unemployment, low education status, poor compliance with medication, and depressive symptoms led to poor QoL.

Conclusion: This study confirms a negative correlation between depressive symptoms and QoL. This study’s results reveal the magnitude of depression that is prevalent in the primary health care clinic that goes undiagnosed and unmanaged. Hence, it is recommended to properly screen depressive symptoms in ACS patients. Therefore, concurrently, better QoL can be achieved by managing both depression and ACS.

Keywords: Acute coronary syndrome, coronary artery diseases, myocardial infarction quality of life, depression, The RAND 36-Item health survey, hamilton depression rating scale.

« Previous Next »
Graphical Abstract

[1]
Fowler, M.B. Beta-blockers in heart failure. Do they improve the quality as well as the quantity of life? Eur. Heart J., 1998, 19(Suppl. P), 17-25.
[PMID: 9886708]
[2]
Lespérance, F.; Frasure-Smith, N. Depression and coronary artery disease: Time to move from observation to trials. CMAJ, 2003, 168(5), 570-571.
[PMID: 12615752]
[3]
Kiessling, A.; Henriksson, P. Perceived cognitive function is a major determinant of health related quality of life in a non-selected population of patients with coronary artery disease--a principal components analysis. Qual. Life Res., 2004, 13(10), 1621-1631.
[http://dx.doi.org/10.1007/s11136-004-7863-0] [PMID: 15651534]
[4]
Megari, K. Quality of life in chronic disease patients. Health Psychol. Res., 2013, 1(3), e27.
[http://dx.doi.org/10.4081/hpr.2013.932] [PMID: 26973912]
[5]
Gierlaszyńska, K.; Pudlo, R.; Jaworska, I.; Byrczek-Godula, K.; Gąsior, M. Tools for assessing quality of life in cardiology and cardiac surgery. Kardiochir. Torakochirurgia Pol., 2016, 13(1), 78-82.
[http://dx.doi.org/10.5114/kitp.2016.58974] [PMID: 27212988]
[6]
Hamilton, M. Development of a rating scale for primary depressive illness. Br. J. Soc. Clin. Psychol., 1967, 6(4), 278-296.
[http://dx.doi.org/10.1111/j.2044-8260.1967.tb00530.x] [PMID: 6080235]
[7]
Spertus, J.A. Evolving applications for patient-centered health status measures. Circulation, 2008, 118(20), 2103-2110.
[http://dx.doi.org/10.1161/CIRCULATIONAHA.107.747568] [PMID: 19001034]
[8]
Rumsfeld, J.S.; Alexander, K.P.; Goff, D.C., Jr; Graham, M.M.; Ho, P.M.; Masoudi, F.A.; Moser, D.K.; Roger, V.L.; Slaughter, M.S.; Smolderen, K.G.; Spertus, J.A.; Sullivan, M.D.; Treat-Jacobson, D.; Zerwic, J.J. Cardiovascular health: The importance of measuring patient-reported health status: A scientific statement from the American Heart Association. Circulation, 2013, 127(22), 2233-2249.
[http://dx.doi.org/10.1161/CIR.0b013e3182949a2e] [PMID: 23648778]
[9]
Blom, M.; Georgiades, A.; László, K.D.; Alinaghizadeh, H.; Janszky, I.; Ahnve, S. Work and marital status in relation to depressive symptoms and social support among women with coronary artery disease. J. Womens Health (Larchmt.), 2007, 16(9), 1305-1316.
[http://dx.doi.org/10.1089/jwh.2006.0191] [PMID: 18001187]
[10]
Luckarinen, H.; Hentinen, M. Assesment of quality of life the Nottingham health profile among patients with coronary heart disease. J. Adv. Nurs., 1997, 26(1), 73-84.
[http://dx.doi.org/10.1046/j.1365-2648.1997.1997026073.x]
[11]
Rude, J.; Azimova, K.; Dominguez, C.; Sarosiek, J.; Edlavitch, S.; Mukherjee, D. Depression as a predictor of length of stay in patients admitted to the cardiovascular intensive care unit at a university medical center. Angiology, 2014, 65(7), 580-584.
[http://dx.doi.org/10.1177/0003319713496868] [PMID: 23897603]
[12]
Ozcanli Atik, D.; Cinar, S. Correlation of cardiovascular limitations and symptoms profile with the quality of life, anxiety and depression scales. Kafkas J. Med. Sci., 2014, 4(2), 51-56.
[http://dx.doi.org/10.5505/kjms.2014.28863]
[13]
Pragodpol, P.; Ryan, C. Critical review of factors predicting health-related quality of life in newly diagnosed coronary artery disease patients. J. Cardiovasc. Nurs., 2013, 28(3), 277-284.
[http://dx.doi.org/10.1097/JCN.0b013e31824af56e] [PMID: 22495801]
[14]
Varghese, T.P.; Kumar, A.V.; Varghese, N.M.; Chand, S. Depression related pathophysiologies relevant in Heart disease: Insight into the mechanism based on pharmacological treatment. Curr. Cardiol. Rev., 2020, 16(2), 125-131.
[http://dx.doi.org/10.2174/1573403X15666191127104520] [PMID: 31775601]
[15]
Lane, D.; Carroll, D.; Ring, C.; Beevers, D.G.; Lip, G.Y. Effects of depression and anxiety on mortality and quality-of-life 4 months after myocardial infarction. J. Psychosom. Res., 2000, 49(4), 229-238.
[http://dx.doi.org/10.1016/S0022-3999(00)00170-7] [PMID: 11119779]
[16]
Malkoff, S.B.; Muldoon, M.F.; Zeigler, Z.R.; Manuck, S.B. Blood platelet responsivity to acute mental stress. Psychosom. Med., 1993, 55(6), 477-482.
[http://dx.doi.org/10.1097/00006842-199311000-00001] [PMID: 8310106]
[17]
Strik, J.J.; Denollet, J.; Lousberg, R.; Honig, A. Comparing symptoms of depression and anxiety as predictors of cardiac events and increased health care consumption after myocardial infarction. J. Am. Coll. Cardiol., 2003, 42(10), 1801-1807.
[http://dx.doi.org/10.1016/j.jacc.2003.07.007] [PMID: 14642691]
[18]
Moryś, J.M.; Bellwon, J.; Höfer, S.; Rynkiewicz, A.; Gruchała, M. Quality of life in patients with coronary heart disease after myocardial infarction and with ischemic heart failure. Arch. Med. Sci., 2016, 12(2), 326-333.
[http://dx.doi.org/10.5114/aoms.2014.47881] [PMID: 27186176]
[19]
Ruo, B.; Rumsfeld, J.S.; Hlatky, M.A.; Liu, H.; Browner, W.S.; Whooley, M.A. Depressive symptoms and health-related quality of life: The Heart and Soul Study. JAMA, 2003, 290(2), 215-221.
[http://dx.doi.org/10.1001/jama.290.2.215] [PMID: 12851276]
[20]
Aghakhani, N.; Sharif, F.; Khademvatam, K.; Rahbar, N.; Eghtedar, S.; Shojaeimotlagh, S.S. The reduction in anxiety and depression by education of patients with myocardial infarction. Int. J. Cardiovasc., 2011, 5, 66-69.
[21]
Unsar, S.; Sut, N.; Durna, Z. Health-related quality of life in patients with coronary artery disease. J. Cardiovasc. Nurs., 2007, 22(6), 501-507.
[http://dx.doi.org/10.1097/01.JCN.0000297382.91131.8d] [PMID: 18090192]
[22]
Westin, L.; Carlsson, R.; Erhardt, L.; Cantor-Graae, E.; McNeil, T. Differences in quality of life in men and women with ischemic heart disease. A prospective controlled study. Scand. Cardiovasc. J., 1999, 33(3), 160-165.
[http://dx.doi.org/10.1080/14017439950141795] [PMID: 10399804]
[23]
Varghese, T.P.; Kumar, A.V. Gender related difference in risk factors and angiographic profile in patients with acute coronary syndrome: a single centre study. Int. J. Pharma Sci., 2018, 9, 268-273.
[24]
Annie, F.H.; Dave, S.; Ahmed, F.; Nanjundappa, A.; Mukherjee, D. The effect of clinical depression on post-TAVI all-cause mortality. Am. J. Cardiol., 2021, 155, 151-152.
[http://dx.doi.org/10.1016/j.amjcard.2021.06.028] [PMID: 34284865]
[25]
Ciccone, M.M.; Aquilino, A.; Cortese, F.; Scicchitano, P.; Sassara, M.; Mola, E.; Rollo, R.; Caldarola, P.; Giorgino, F.; Pomo, V.; Bux, F. Feasibility and effectiveness of a disease and care management model in the primary health care system for patients with heart failure and diabetes (Project Leonardo). Vasc. Health Risk Manag., 2010, 6, 297-305.
[http://dx.doi.org/10.2147/VHRM.S9252] [PMID: 20479952]
[26]
Palur Ramakrishnan, A.V.; Varghese, T.P.; Vanapalli, S.; Nair, N.K.; Mingate, M.D. Platelet activating factor: A potential biomarker in acute coronary syndrome? Cardiovasc. Ther., 2017, 35(1), 64-70.
[http://dx.doi.org/10.1111/1755-5922.12233] [PMID: 27790832]
[27]
Varghese, T.P.; Pannayapan, L.; Krishnakumar, K.; George, L. A prospective study on the risk factors, angiographic severity and their correlation with STEMI and NSTEMI in patient with acute coronary symptoms. Harmoniz. Res. Med. Health Sci., 2015, 2(1), 1-5.
[28]
Varghese, T.P.; Kumar, A.V. Predisposing risk factors of acute coronary syndrome (ACS): A mini review. J. Pharm. Sci. Res., 2019, 11, 1999-02.

Rights & Permissions Print Cite
Article Metrics
30
3
Wayfinder Image
© 2024 Bentham Science Publishers | Privacy Policy